Results 161 to 170 of about 7,180,624 (308)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

On Dependent Variables in Reactive Synthesis

AbstractGiven a Linear Temporal Logic (LTL) formula over input and output variables, reactive synthesis requires us to design a deterministic Mealy machine that gives the values of outputs at every time step for every sequence of inputs, such that the LTL formula is satisfied.
S. Akshay 0001, Eliyahu Basa, Supratik Chakraborty, Dror Fried   +3 more
openaire   +2 more sources

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

FEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan, Avi Singh, Shrawani Weralupe Gamladdalage, Joanna Hicks, Adele Williamson   +4 more
wiley   +1 more source

Numerical simulation of proppant transport in hydraulic fractures with length-dependent variable aperture. [PDF]

Sci Rep
Xiao H, Yuan C, Wang C, Shi G, Wan Q, Gao G, Zhang M.   +6 more
europepmc   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Antiepileptic drugs in glioblastoma survival: dichotomic or treatment and mechanism of action-dependent variable? [PDF]

Neurooncol Adv
Genel O, Alzarouni S, Mirza AB, Ghimire P, Murden S, Chowdhury YA, Elhag A, Cikurel K, Joe D, Finnerty G, Manik V, Swampillai A, Al-Salihi O, Chia K, Brazil L, Forner S, Glendenning J, Gullan R, Ashkan K, Bhangoo R, Vergani F, Lavrador JP.   +21 more
europepmc   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

NIR-Based Adulteration Screening of <i>Rubus chingii</i> Hu: A Two-Dimensional Correlation Spectroscopy-Guided Chemometric Strategy with Model-Dependent Variable Selection. [PDF]

Foods
Wang Y, Wang Y, Chen Y.
europepmc   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Multivariable regression summary (dependent variable is WATP, in USD.

Multivariable regression summary (dependent variable is WATP, in USD.
Rafael Mikolajczyk (43665), Damen Hailemariam (506982), Birgit Silbersack (18126698), Pablo Santos (298511), Eric Sven Kroeber (12979935), Susanne Unverzagt (301872), Eva Johanna Kantelhardt (4683103), Edom Seife (11161818), Tamiru Demeke (9713827), Adamu Addissie (3180735)   +9 more
core   +1 more source