Results 281 to 290 of about 302,258 (333)

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

open access: yesAdvanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li   +9 more
wiley   +1 more source

Neuronal activity-dependent gene dysregulation in <i>C9orf72</i> i<sup>3</sup>Neuronal models of ALS/FTD pathogenesis. [PDF]

open access: yesAm J Physiol Cell Physiol
Ghaffari LT   +7 more
europepmc   +1 more source

Microglial Membranes Wrapped Ultrasmall Medium‐Entropy Ru Single‐Atom Nanozyme: Enhanced Catalysis for Accelerating Inflammation/Redox Microenvironment Regulation in Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
PtRhIr/Ru SAN@M nanozymes cross the blood–brain barrier and selectively accumulate in hemorrhagic brain regions. By mimicking multiple enzyme activities, they attenuate oxidative stress, modulate microglial polarization toward an anti‐inflammatory phenotype, inhibit ferroptosis, and promote neuronal repair.
Jiebo Li   +17 more
wiley   +1 more source

Effect of hypoxia and KCl depolarization in autofluorescence and ROS changes at the hippocampal CA3 area

open access: diamond
Marta Iwanaszko   +9 more
openalex   +2 more sources

Methodological validation of Miro1 retention as a candidate Parkinson's disease biomarker. [PDF]

open access: yesNPJ Parkinsons Dis
Drwesh L   +12 more
europepmc   +1 more source

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