Results 301 to 310 of about 254,537 (363)

Annihilation of action potentials induces electrical coupling between neurons. [PDF]

Elife
Schloetter M, Maret GU, Kleineidam CJ.
europepmc   +1 more source

SAAP‐148 oligomerizes into a hexamer forming a hydrophobic inner core

ChemBioChem, Accepted Article.
Human cathelicidin LL‐37 is a widely studied antimicrobial 37‐mer peptide with various ascribed functions, that serves as a template for designing novel peptides. Its derivative, the 24‐mer SAAP‐148, is highly effective in vitro in eradicating multidrug‐resistant bacteria, persistent cells, and biofilms, without inducing resistance.
Nermina Malanovic, Aden Hodzic, Djenana Vejzovic, Altea Topciu, Kirill Kuhlmann, Raj Kumar, Maria Andrea Mroginski, Alejandra Andrea de Miguel, Pia Hofmann, Klaus Zangger, Markus Weingarth, Robert A. Cordfunke, Jan W. Drijfhout, Peter Nibbering, Michal Belicka, Karl Lohner   +15 more
wiley   +1 more source

Secretory mitophagy: an extracellular vesicle-mediated adaptive mechanism for cancer cell survival under oxidative stress. [PDF]

Front Cell Dev Biol
Gade PV, Rivera AVR, Hasanzadah L, Strompf S, Philipson TR, Gadziala M, Tyagi A, Bandam A, Gabbireddy R, Kashanchi F, Haymond A, Liotta LA, Howard MA.   +12 more
europepmc   +1 more source

A Further Study of the Motoneuron-Depolarizing Peptide Extracted from Dorsal Roots of Bovine Spinal Nerves

, 1972
Masanori Otsuka, Shiro Konishi, Tomoyuki Takahashi   +2 more
openalex   +2 more sources

Macrocycles of Saxitoxin: Insights into the Structure of Zetekitoxin AB

ChemBioChem, EarlyView.
Synthetic macrocycles of (+)‐saxitoxin, the causative agent of paralytic shellfish poisoning, have been prepared. These are designed to mimic the macrocyclic core of the proposed structure for zetekitoxin AB. Interestingly, these synthetic macrocycles do not form the C12 hydrate as commonly observed in this family of toxins, casting doubt on the ...
Wenyuan Li, Srinivas R. Paladugu, Jordan P. Liles, Manju Karthikeyan, Kevin Chase, Shrinivasan Raghuraman, Matthew S. Sigman, Ryan E. Looper   +7 more
wiley   +1 more source

Genotype-function-phenotype correlations for SCN1A variants identified by clinical genetic testing. [PDF]

Ann Clin Transl Neurol
Knox AT, Thompson CH, Scott D, Abramova TV, Stieve B, Freeman A, George AL.   +6 more
europepmc   +1 more source

A Proteomics Profiling Reveals the Neuroprotective Effects of Melatonin on Exogenous β‐amyloid‐42 Induced Mitochondrial Impairment, Intracellular β‐amyloid Accumulation and Tau Hyperphosphorylation in Human SH‐SY5Y Cells

Cell Biology International, EarlyView.
ABSTRACT Alzheimer's disease (AD) is prevalent in the elderly population and characterized by the intracellular accumulation of neurofibrillary tangles (NFTs), composed of tau proteins, and extracellular deposition of beta‐amyloid protein (Aβ). The present study aimed to investigate the neuroprotective effects of melatonin on Aβ42‐induced AD‐like ...
Jiraporn Panmanee, Matthew Phanchana, Phorutai Pearngam, Nopphon Petchyam, Kornkanok Promthep, Ponlawit Wisomka, Suchanoot Kutpruek, Supitcha Pannengpetch, Tanya Prasertporn, Sujira Mukda, Piyarat Govitrapong, Chutikorn Nopparat   +11 more
wiley   +1 more source

Actin maintains synaptic transmission by restraining vesicle release probability. [PDF]

iScience
Wu XS, Zhang Z, Jin Y, Mushtaheed A, Wu LG.   +4 more
europepmc   +1 more source

Mitochondria‐Catalyzed Activation of Anticancer Prodrugs

ChemCatChem, Accepted Article.
Mitochondria mediate electron transport chain (ETC) to power ATP synthase. In cancer cells, the ETC is disturbed leading to leakage of electron that ultimately results in generation of H2O2. This difference between cancer and healthy cells can be used for the design of cancer‐specific prodrugs as confirmed in several proof‐of‐concept studies ...
Michael Raucheisen, Dina Attia, Marlies Körber, Alejandra Aroca Crevillén, Andrés Hidalgo, Frank Beierlein, Petra Imhof, Andriy Mokhir   +7 more
wiley   +1 more source

Stress Cardiomyopathy Following Multivisceral Transplantation: A Case Report. [PDF]

Cureus
Souki FG, Caram N, Fouda E, Nicolau-Raducu R.   +3 more
europepmc   +1 more source