Results 61 to 70 of about 2,323 (236)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

CREDIT MANAGEMENT PRACTICES, FIRM SIZE AND FINANCIAL SUSTAINABILITY OF DEPOSIT TAKING SAVINGS AND CREDIT COOPERATIVE SOCIETIES IN KENYA [PDF]

open access: yesFinancial Studies
The study examined the moderating effect of firm size on the relationship between credit management practices and the financial sustainability of DT-SACCOs in Kenya.
John Ndung'u GACHENGA   +2 more
doaj  

CONSIDERATIONS REGARDING THE CREATION OF A EUROPEAN BANKING UNION – A KEY ELEMENT IN REINFORCING THE BANKING SYSTEM [PDF]

open access: yesChallenges of the Knowledge Society, 2015
The idea of setting up a European Banking Union, an essential element in the reinforcement of the Economic and Monetary Union (EMU), has become a concrete project and it has been outlined as such after the financial crisis started in 2007. The setting up
Mădălina Antoaneta RĂDOI   +1 more
doaj  

FEATURES OF THE BANKING DEPOSITS GUARANTEE FUNDS IN THE EUROPEAN COUNTRIES [PDF]

open access: yesAnalele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2015
The aim of this paper is to present a comparative approach of the deposit guarantee funds in different European countries for underlying the advantages or disadvantages for the banking systems and the features of these funds so we can conclude which one is better for the deponents and for the banking systems as a whole.
openaire   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

The Security of Formation and Use of Means of the Deposit Guarantee Fund

open access: yesBìznes Inform, 2018
The article is aimed at improving the theoretical and methodical approaches to the formation and use of DGF resources in the context of compliance with financial security. On the basis of the analysis and evaluation of the existing tendencies of development of the system of deposit guarantee in Ukraine, the basic principles and problematic aspects of ...
Kopylyuk Oksana I.   +2 more
openaire   +1 more source

The Australian Government Guarantee Scheme for Large Deposits and Wholesale Funding (Australia GFC)

open access: yesJournal of Financial Crises, 2020
The Australian Guarantee Scheme for Large Deposits and Wholesale Funding was developed in 2008 shortly after the failure of Lehman Brothers. It was designed to foster financial-system stability and confidence and to help depository institutions continue to access funding during a period of volatility.
openaire   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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