Results 111 to 120 of about 1,600,082 (335)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Weathering and erosion of the polar layered deposits on Mars [PDF]

open access: yes
The Martial polar layered deposits are widely believed to be composed of water ice and silicates, but the relative amount of each component is unknown. The conventional wisdom among Mars researchers is that the deposits were formed by periodic variations
Herkenhoff, K. E.
core   +1 more source

Software Deposit: What To Deposit

open access: yes, 2018
What do we mean by a "software deposit"? What does a software deposit need to contain to enable it to allow other researchers to inspect, replicate, reproduce and reuse the research, as manifested in the software, in the short term and inspect the software, for the historical record, in the long term. This guide describes what a software deposit should
openaire   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Research of Deposit Accumulated on Heat Exchange Surfaces in the Light of Thermal Degradation of Heat Exchange Aparatus of Steam Power Plants Part I: Study of Real Sediments

open access: yesPolish Maritime Research, 2018
The presence of deposits on heat exchange surfaces in condensers and regenerative exchangers of ship and land steam power plants is always connected with the increase of the wall temperature on the water vapor side due to additional thermal resistances ...
Hajduk Tomasz
doaj   +1 more source

Requiem for Regulation Q: what it did and why it passed away [PDF]

open access: yes
Regulation Q: Prohibition Against Payment of Interest on Demand Deposits ; Bank deposits ...
R. Alton Gilbert
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

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