Results 81 to 90 of about 1,588,539 (338)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Оn the selection of an aquifer as an absorbing reservoir for the disposal of industrial wastewater
Наука. Инновации. ТехнологииThe article presents the collection, generalization and analysis of geological and field data, as well as the consideration of geological and hydrogeological conditions for underground disposal of wastewater, with the justification of the choice of an ...
R.A. Gasumov, E. R. Gasumov
doaj +1 more source
Vojnotehnički Glasnik, 2016 Donošenje odluka o prostornom raspoređivanju opasnih materija neophodno je zbog minimiziranja rizika po okolinu. U ovom radu razmatran je problem lociranja različitih vrsta opasnih materija (sa različitim karakteristikama).
Branka S. Dimitrijević +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
NATURAL RESOURCES – A REAL OR HYPOTHETICAL OBJECT OF ACCOUNTING [PDF]
Scientific Papers Series : Management, Economic Engineering in Agriculture and Rural Development, 2013 Nowadays natural resources have a controversial accounting treatment which is caused, firstly, by neglecting their inherent properties and, secondly, by a free and one-sided interpretation of the legal framework.
Alexandru FRECAUTEANU, Angela CHISLARU
doaj
Natural history specimens collected and/or identified and deposited.
, 2021 Jack Schuster
openalex +2 more sources
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Software Deposit: What To Deposit
, 2018 What do we mean by a "software deposit"? What does a software deposit need to contain to enable it to allow other researchers to inspect, replicate, reproduce and reuse the research, as manifested in the software, in the short term and inspect the software, for the historical record, in the long term. This guide describes what a software deposit should
openaire +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source