Results 81 to 90 of about 507,597 (315)
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Manganese deposits of the Cape Peninsula, South Africa
, 2013 The outcrops, petrography and geochemistry of manganese deposits were studied at several sites on the Cape Peninsula (Skeleton Gorge, Kasteelpoort Path, Kommetjie and Hout Bay) as well as at Rooi Els on the opposite side of False Bay.
MacGregor, Duncan Graeme
core
Dense deposit disease involving C3 and C4d Deposits
Indian Journal of Nephrology, 2018 Dense deposit disease (DDD), earlier called Type II membranoproliferative glomerulonephritis is distinct disease having frequent relapses reaching end-stage kidney disease by 10-year in up to 50%-60% of cases and high recurrence rate in the allograft. The term DDD is derived from its distinctive ribbon-like osmiophilic deposits in the lamina densa of ...
Vankalakunti, M. +6 more
openaire +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Preferencje w zakresie form alokacji oszczędności gospodarstw domowych w Polsce
Copernican Journal of Finance & Accounting, 2013 Celem artykułu jest analiza preferencji w z akresie form alokacji oszczędności gospodarstw domowych w Polsce. Polacy najczęściej oszczędzają w instytucjach bankowych w depozytach złotowych.
Dorota Krupa +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Barite Deposits of Türkiye: A Review
Türkiye hosts a wide variety of barite deposits that can be broadly classified into two major groups based on their tectonic settings: magmatism-associated and passive margin-hosted deposits.
Nurullah Hanilçi +2 more
core +1 more source
, 2022 Hydrothermal quartz samples collected from the Fujiashan and Yipanqiu quartz deposits in southeastern Hubei Province, China have been investigated by analytical combination of optical microscopy, scanning electron microscopy, and inductively coupled ...
Yufei Hu +3 more
core +1 more source