Results 151 to 160 of about 2,071 (262)

External Control Arms in Japan: A Systematic Case Analysis of Documented Regulatory Implementation and Uncertainty Management

Clinical Pharmacology &Therapeutics, EarlyView.
External control arms (ECAs) have emerged as important tools to provide benchmark evidence on comparator effectiveness and thereby support regulatory decision making in situations where randomized controlled trials are difficult to conduct. However, how key methodological elements for ECAs are documented and implemented in practice and how residual ...
Suguru Okami, Alexandros Sagkriotis
wiley   +1 more source

A Functional Response in Resource Selection Links Multiscale Responses of a Large Carnivore to Human Mortality Risk. [PDF]

Ecol Lett
Dougherty KD, Dellinger JA, Cristescu B, Gammons DJ, Garcelon DK, Higley JM, Martins QE, Riley SPD, Sikich JA, Stephenson TR, Vickers TW, Wengert GM, Wilmers CC, Wittmer HU, Benson JF.   +14 more
europepmc   +1 more source

Biography as the Missing Variable in Drug Development: A Case for Bio‐Biographical Mechanistic Profiling

Clinical Pharmacology &Therapeutics, EarlyView.
Most clinical trial failures reflect unmeasured biological heterogeneity. Biography — chronic stress, adversity, trauma, and social isolation—is a neglected source of that heterogeneity, operating through the same molecular pathways drugs engage.
Ralph I. Horwitz
wiley   +1 more source

Human-wildlife conflict is amplified during periods of drought. [PDF]

Sci Adv
Calhoun KL, Smith JA, Tingley MW, Heeren A, Van Scoyoc A, Serota MW, Brashares JS, Furnas BJ.   +7 more
europepmc   +1 more source

Mapping the US Bridgebuilding Field: Situating Organizations in the Ecosystem of Social Change

Conflict Resolution Quarterly, EarlyView.
ABSTRACT This article explores the ecosystem of bridge‐building initiatives in the United States. Drawing on an original database of 223 organizations, interviews with 7 staff across 6 organizations, and a literature review related to bridge‐building, polarization, and collective action, we first describe the range of existing initiatives and their ...
Gabrielle Mathews, Karen Ross
wiley   +1 more source

Multi-Source Remote Sensing and Ensemble Learning for Habitat Suitability Mapping of the Common Leopard (<i>Panthera pardus</i>) in Azad Jammu and Kashmir, Pakistan. [PDF]

Sensors (Basel)
Dildar Z, Huang W, Ahmed R, Khalid Z.
europepmc   +1 more source

Sustainability Disclosure and External Assurance of Reports in the Italian Agrifood Sector

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The European Union introduced the Corporate Sustainability Reporting Directive (CSRD) with the aim of aligning the “walk”—the implementation of substantive sustainability practices—and the “talk”—their representation in sustainability reporting.
Andrea Caccialanza, Mirta Casati, Marco Angelo Marinoni   +2 more
wiley   +1 more source

Beyond kill or no-kill: Institutional analysis of lethal control decision-making in large carnivore management. [PDF]

Ambio
Srivastava N, Linnell JDC, Krishnamurthy R, Koenig HJ, Fürst C.   +4 more
europepmc   +1 more source

Corporate Social Responsibility and Corporate Tax Avoidance in Europe: Evidence From the Anti‐Tax Avoidance Directives

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the relationship between corporate social responsibility (CSR) and corporate tax avoidance (CTA) in the European Union, exploiting institutional variation arising from CSR disclosure regimes and the introduction of the Anti‐Tax Avoidance Directives (ATAD).
Alessandro Migliavacca
wiley   +1 more source

Does ESG Drive Performance or Does Performance Enable ESG? Evidence of Reverse Causality From Korean Firms

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT The Environmental, Social, and Governance (ESG)‐performance literature has grown substantially, yet a fundamental question remains underexplored: do ESG investments improve firm performance, or do high‐performing firms simply invest more in ESG? We empirically address this question using panel vector autoregression with Granger causality tests
Jiyeon Kim, Wooyoung Yang
wiley   +1 more source