Results 61 to 70 of about 1,163 (152)

Appropriate medication use in Dutch terminal care:study protocol of a multicentre stepped-wedge cluster randomized controlled trial (the AMUSE study) [PDF]

Background: Polypharmacy is common among patients with a limited life expectancy, even shortly before death. This is partly inevitable, because these patients often have multiple symptoms which need to be alleviated.
de Jong, M.A.C., Geijteman, E C T, Kiers, J N A, Oomen-de Hoop, E, Pot, I E, Thijs-Visser, M F, van den Homberg, P.P.P.H., van der Heide, A, van der Kuy, P H M, van der Rijt, C C D, van der Vorst, M.J.D.L., van Hylckama Vlieg, M A M, van Mastrigt, B J, Visser, H P J   +13 more
core   +4 more sources

Analysis of Psychotropic Polypharmacy and Associated Factors in Antidepressant‐Treated Patients With Depressive Disorder: A Population‐Based Cohort Study Using Real World Data

Depression and Anxiety, Volume 2026, Issue 1, 2026.
Introduction Psychotropic polypharmacy typically refers to the prescription of more than one psychotropic medication to a patient. While polypharmacy can sometimes be clinically justified, it is widely recognized that multiple drug use and exposure can be problematic.
Diego Infante-Ventura, Benjamín Rodríguez-Díaz, Miguel Ángel García-Bello, Cristina Válcarcel-Nazco, Francisco Estupiñán-Romero, Francisco Javier Acosta Artiles, Beatriz González de León, Isabel Hurtado-Navarro, Tasmania del Pino-Sedeño, Marie Kristin Manthey   +9 more
wiley   +1 more source

Appropriateness and Outcome of a Statin Deprescription Intervention in Hospitalized Frail Older Adults: A Retrospective Study

Geriatrics
Background/Objectives: The appropriateness of statin treatment in frail older adults is controversial because of insufficient evidence on its efficacy.
Giuseppe Castiglia, Nicola Veronese, Gianluca Gortan Cappellari, Erica Voinovich, Paolo De Colle, Michela Zanetti   +5 more
doaj   +1 more source

Barriers to Opioid Deprescription in Rural Newfoundland and Labrador: Findings from Pilot Interviews with Rural Family Physicians [PDF]

, 2020
Background: Medical doctors in Canada have a lack of education and understanding on how to safely prescribe opioids. Rural areas and Aboriginal populations have been identified as being at greater risk for opioid misuse. The purpose of this pilot project
Asghari, Shabnam, Heeley, Thomas, MacLean, Cassandra, Versteeg, Everett   +3 more
core  

Experiences and Perceptions of Care for Medications With a Risk of Dependence: Insights From Patients and Healthcare Professionals

Health &Social Care in the Community, Volume 2026, Issue 1, 2026.
Background Medications with a risk of dependence are widely prescribed but have been associated with a poor experience of care for patients. This study aimed to understand patient and healthcare staff perspectives in the prescription, management, and deprescription of benzodiazepines, z‐drugs, opioids for chronic noncancer pain, gabapentinoids, and ...
Jennifer Seddon, Claire Friedrich, David Dicks, Sion Scott, Anthea Robinson, Charlotte Walker, Sarah Wadd, Mohammad Niroumand Sarvandani   +7 more
wiley   +1 more source

A multi- and mixed-method adaptation study of a patient-centered perioperative mental health intervention bundle [PDF]

, 2023
BACKGROUND: Anxiety and depression are common among older adults and can intensify during perioperative periods, but few mental health interventions are designed for older surgical patients\u27 unique needs. As part of the feasibility trial, we developed
Abraham, Joanna, Avidan, Michael S, Baumann, Ana, Freedland, Kenneth E, Holzer, Katherine J, Lenard, Emily, Lenze, Eric J, Meng, Alicia, Politi, Mary C   +8 more
core   +2 more sources

The synergistic effect of anticholinergic burden and depression on fall risk in older persons

British Journal of Clinical Pharmacology, Volume 91, Issue 11, Page 3082-3091, November 2025.
Aims Both anticholinergic burden (ACB) and depression are known to increase fall risk in older persons, next to increasing morbidity and mortality. However, the effect of depression on fall risk associated with ACB is unclear. This is relevant because several antidepressants have anticholinergic effects to some extent.
Raymond Salet, Nathalie van der Velde, Didi Rhebergen, Bob van de Loo, Lotta Seppala, Natasja M. van Schoor, Bruno Stricker, Marieke Henstra   +7 more
wiley   +1 more source

Deprescribing: Less is More for Elderly Patients? [PDF]

, 2023
published_or_final_versio
Kong, Tak Kwan
core  

Prevalence, Characteristics and Determinants of Polypharmacy Among Elderly Patients Attending Primary Health Care Centers in Bahrain: A cross-sectional study [PDF]

, 2023
Objectives: This study aims to determine the prevalence, characteristics and determinants of polypharmacy among elderly patients in Bahrain. Methods: A cross-sectional study was conducted in the period between March and April 2022 in all primary ...
Al-Buainain, Muneera, Alawainati, Mahmood, Ateya, Eman, Dakheel, Eman, Habib, Fatima   +4 more
core   +2 more sources

A geriatrician's approach to managing the complex older adult with obesity

Obesity, Volume 33, Issue S1, Page 41-56, November 2025.
Abstract The prevalence of obesity in older adults is rapidly increasing due to the demographic shift occurring globally. Older adults with obesity face health care challenges due to multimorbidity, functional dependency, and disability. This population often has prior history of struggles through weight‐loss attempts during the middle years of life ...
Shenbagam Dewar
wiley   +1 more source