Results 181 to 190 of about 1,368 (214)

Effect of beta blockers in acute and chronic coronary syndromes without reduced ejection fraction: a landmark analysis from the REBOOT trial.

European Heart Journal - Cardiovascular Pharmacotherapy
BACKGROUND AND AIMS Current guidelines recommend beta-blocker therapy after myocardial infarction (MI) regardless of left ventricular ejection fraction (LVEF). However, recent trials question their benefit in patients with preserved LVEF.
Xavier Rosselló, J. A. Barrabés, Massimo Piepoli, Alberto Domínguez-Rodríguez, P. L. Sánchez, Manuel Anguita, S. Raposeiras-Roubín, Giulietta Grigis, Jaume Agüero, Ruth Owen, S. Pocock, Carlos Nicolás Pérez-García, Noemí Escalera, Andrea Kallmeyer, A. Sionis, L. Staszewsky, Alfonso Torres, Rocio Barquero, F. Fernández-Vázquez, Francisco Marín, A. Vetrano, Pablo Pastor, Valentín Fuster, Roberto Latini, Borja Ibáñez   +24 more
semanticscholar   +1 more source

Clinical impact of cardiac magnetic resonance imaging in myocardial infarction with non-obstructive coronary arteries: a prospective multicentre cohort study

Heart
Background Cardiac magnetic resonance (CMR) may radiologically identify or confirm underlying pathophysiologies in myocardial infarction with non-obstructive coronary arteries (MINOCA), however, there are scant prospective data evaluating the impact on ...
Adil Rajwani, L. Giudicatti, P. Telyuk, N. Maredia, Abdul Ihdayhid, D. Chieng, S. Pasupathy, John F. Beltrame, B. McQuillan, Jon Spiro, Carl Schultz, G. Hillis, Dave Austin, Girish Dwivedi   +13 more
semanticscholar   +1 more source

Antipsychotic Deprescription for Older Adults in Long-term Care: The HALT Study

Journal of the American Medical Directors Association, 2018
Despite limited efficacy and significant safety concerns, antipsychotic medications are frequently used to treat behavioral and psychological symptoms of dementia (BPSD) in long-term residential care. This study evaluates the sustained reduction of antipsychotic use for BPSD through a deprescribing intervention and education of health care ...
Henry Brodaty, Liesbeth Aerts, Fleur Harrison, Tiffany Jessop, Monica Cations, Lynn Chenoweth, Allan Shell, Gordana C. Popovic, Megan Heffernan, Sarah Hilmer, Perminder S. Sachdev, Brian Draper   +11 more
openaire   +2 more sources

La déprescription en médecine générale. Une revue ciblée de la littérature française

EXERCER
Contexte. La polymédication associée au vieillissement de la population entraîne un risque de prescriptions médicamenteuses inappropriées. Celles-ci sont responsables d’effets indésirables graves et de conséquences économiques pour les patients et la ...
J. NGUYEN-SOENEN, JP Fournier, P. LE LAGADEC, T. Morel   +3 more
semanticscholar   +1 more source

Increased rates of proton pump inhibitor deprescription: a retrospective cohort of patients with upper gastrointestinal bleeding requiring endoscopic intervention

Journal of the Canadian Association of Gastroenterology
Objective Proton pump inhibitors (PPIs) are widely prescribed but inappropriate indications and concerns over long-term side effects have led to recommendations to deprescribe PPIs in certain patients.
K. Kecskemeti, M. Borgaonkar, J. Mcgrath
semanticscholar   +1 more source

Prolonged use of benzodiazepine in primary health care: evaluation of effectiveness, dependence and cognitive function.

Expert Opinion on Drug Safety
BACKGROUND Anxiety and insomnia are global health challenges often managed in Primary Health Care (PHC). Benzodiazepines (BZD) are commonly prescribed, but prolonged use increases risks such as cognitive impairment, dependence, and tolerance.
Júlia Casanova Durante, Amanda Gomes Dantas, Fabiana Coelho Inouye, F. Varallo, Leonardo Régis Leira Pereira, Adriana Inocenti Miasso, Marília Silveira de Almeida, Maria Olívia Barboza Zanetti   +7 more
semanticscholar   +1 more source

Description of barriers to the deprescription of inappropriate drugs in French hospitalized geriatric services

Scientific Reports
In France, drug-related iatrogenesis is considered to be the cause of numerous emergency departments consultations and the onset of many disabling comorbidities in elderly people.
C. Antoniazzi, X. Cnockaert, P. Michel
semanticscholar   +1 more source

Optimizing Use of Antithrombotics and Overcoming Therapeutic Inertia: Lessons from the AEGIS Trial

Thrombosis and Haemostasis
Therapeutic inertia and therapeutic momentum, de fi ned as continuing prescription of drugs without periodic review of their indications and bene fi ts, and the addition of new drugs in response to new, debatable indications (which can include side effects
G. F. Romiti
semanticscholar   +1 more source

Re-Audit of Safe Deprescribing on Inpatient Psychiatric Wards After Implementation of an Electronic Prescribing Management and Administration (EPMA) System in an NHS Trust

BJPsych Open
Aims: The audit aimed to evaluate the effectiveness of transitioning from paper-based patient prescription charts (Kardex) to an electronic prescribing and medication administration system (EPMA) in improving compliance with safe deprescribing practices ...
Udoka Onyechere, Toibat Adeyinka, Harvir Sahota   +2 more
semanticscholar   +1 more source

Targeted Deprescribing in an Outpatient Hemodialysis Unit: A Quality Improvement Study to Decrease Polypharmacy.

American Journal of Kidney Diseases, 2017
C. McIntyre, R. McQuillan, C. Bell, M. Battistella   +3 more
semanticscholar   +1 more source