Results 11 to 20 of about 1,020 (190)

Development and validation of search filters to identify articles on deprescribing in Medline and Embase [PDF]

BMC Medical Research Methodology, 2022
Background Deprescribing literature has been increasing rapidly. Our aim was to develop and validate search filters to identify articles on deprescribing in Medline via PubMed and in Embase via Embase.com . Methods Articles published from 2011 to 2020 in
Thomas Morel, Jérôme Nguyen-Soenen, Wade Thompson, Jean-Pascal Fournier   +3 more
doaj   +2 more sources

Deprescribing in Older People: A Clinical Practice Guideline Summary. [PDF]

Med J Aust
ABSTRACT Introduction Older people face higher risks of medicine‐related harm due to polypharmacy and the use of potentially inappropriate medicines. Current treatment guidelines rarely specify when to stop medicines, leading to medicines often being continued indefinitely without a clear deprescribing plan.
Quek HW, Reus Perello X, Lee K, Abraham A, Adams LA, Almeida OP, Almutairi H, Armstrong B, Boase L, Breen J, Brown LJ, Caughey GE, Chan LW, Chen R, Chew E, Clark A, Comans T, Criddle D, Dārziņš P, Dawda P, Doust JA, Edwards S, Gowan J, Hart K, Hawthorne D, Heredia A, Hill AM, Jansen J, Kalisch Ellett L, Keen H, Kelty EA, Kerse NM, Kruger E, Kurrle SE, Lance H, Livori A, Livori R, LoGiudice DC, Mangoni AA, Marinucci A, McKay N, Mckendrick AM, McLachlan AJ, McGuire TM, Mearns S, Morgan M, Nabi S, Naganathan V, Newman E, Ng CACM, Osborne M, Parkin R, Polkinghorne KR, Pond CD, Potter K, Rigby D, Rowett D, Schipp A, Seda V, Seeto J, Shakib S, Shiu A, Stafford AC, Tan IJ, Tennant M, Teoh L, Tucker S, Watson JDG, Wellins D, Whitmore T, Etherton-Beer C, Page AT.   +71 more
europepmc   +2 more sources

Insights Into Pharmacist-Led Deprescribing of Benzodiazepines and Related Drugs: A Qualitative Study With Physicians and Pharmacists. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT While deprescribing benzodiazepines and related drugs (BZRDs) is crucial for preventing prolonged use and their associated adverse effects, it presents challenges from a healthcare perspective, because of limited resources and time. Recently, a pharmacist‐led deprescribing of BZRDs in the treatment of insomnia was introduced in Helsinki's ...
Korppas M, Tiihonen M, Buch Lund M, Kvarnström K.   +3 more
europepmc   +2 more sources

Tailoring a complex intervention to reduce antidepressants in institutionalized older persons with dementia [PDF]

BMC Health Services Research, 2022
Introduction First-line treatment for behavioral and psychiatric symptoms of dementia is non-pharmacological. Still, psychotropic medication is widely used, despite its limited effect and harmful side-effects. More than half of all nursing home residents
Pernille Hølmkjær, Charlotte Vermehren, Anne Holm, Maarten Pieter Rozing, Kirsten Høj, Gritt Overbeck   +5 more
doaj   +3 more sources

The I-Learn Cognition and Behavior program for non-pharmacological treatment of agitation in nursing home residents with neurocognitive disorders: A cluster randomized trial. [PDF]

Alzheimers Dement (N Y)
Abstract INTRODUCTION The “I‐Learn Cognition and Behavior” program, integrating e‐learning and simulation, aims to equip long‐term care facility staff with non‐pharmacological approaches for managing agitation in residents with neurocognitive disorders. This study evaluated the program's effectiveness.
Lourdel C, Launay A, Couteau A, Bomia D, Pointereau S, Bulteau S, Tessier F, Thevenet S, Ahoure C, Belloeil V, Robert G, Taudin N, Manivel L, Daucé-Fleuret L, Richomme C, Camus V, Brit S, Léger J, Desmidt T.   +18 more
europepmc   +2 more sources

Internet and telephone intervention to support patients discontinuing long-term antidepressants in primary care: the REDUCE research programme including RCT

Programme Grants for Applied Research
Background There is significant concern about increasing long-term antidepressant use in Western countries, much of which is not evidence-based. Median duration of treatment is more than 2 years in the United Kingdom, and more than 10% of adults are ...
Tony Kendrick, Beth Stuart, Hannah Bowers, Mahboobeh Haji Sadeghi, Helen Page, Christopher Dowrick, Michael Moore, Mark Gabbay, Geraldine Leydon, Guiqing Lily Yao, Shihua Zhu, Paul Little, Gareth Griffiths, Glyn Lewis, Carl May, Joanna Moncrieff, Chris F Johnson, Una Macleod, Simon Gilbody, Rachel Dewar-Haggart, Samantha Williams, Wendy O’Brien, Riya Tiwari, Catherine Woods, Tasneem Patel, Naila Khan, Emma Maund, Nadja van Ginneken, Amy Din, Claire Reidy, Rebecca Lucier, Bryan Palmer, Taeko Becque, Yumna Masood, Natalie Thompson, Ellen van Leeuwen, Marta Glowacka, Adam WA Geraghty   +37 more
doaj   +2 more sources

Drug deprescription—withdrawal risk, prevention, and treatment [PDF]

Baylor University Medical Center Proceedings, 2020
In most cases, a sudden interruption of most medications has no major consequences. There are well-recognized therapies that, when withheld, can either lead to the reappearance of the symptoms they were controlling or to signs or symptoms of withdrawal ...
Gabriel M Aisenberg
exaly   +2 more sources

Deprescribing Benzodiazepine Receptor Agonists in Older Adults and People With Cognitive Impairment: A Systematic Review. [PDF]

J Am Geriatr Soc
ABSTRACT Background Benzodiazepine receptor agonists (BZRAs) (benzodiazepines and z‐drugs) may provide limited benefits in the management of insomnia when used short‐term. However, they increase the risk of harms including falls, fractures, hospitalizations, and cognitive impairment. Deprescribing (cessation) of BZRAs may be beneficial for older adults
McEvoy AM, Langford AV, Liau SJ, Goordeen D, Reeve E, Turner JP.   +5 more
europepmc   +2 more sources

Deprescribing psychoactive drugs in older orthogeriatric patients: findings from the GIOG2.0 Italian survey [PDF]

BMC Geriatrics
Background Psychoactive drugs represent a major contributor to falls in older people. This study aims to evaluate the prescribing practice of psychoactive drugs in older people hospitalized for hip fracture (HF) and to explore independent correlates of ...
Andrea Cavalli, Antonio De Vincentis, Claudio Pedone, Alice Laudisio, Lucrezia Santoro, Maria Cristina Ferrara, Caterina Trevisan, Elena Tassistro, Maria Grazia Valsecchi, Giuseppe Castoldi, Chiara Mussi, Giuseppe Sergi, Andrea Ungar, Stefano Volpato, Rocco Papalia, Raffaele Antonelli Incalzi, Giuseppe Bellelli   +16 more
doaj   +2 more sources

Prescriptive Appropriateness: Inhospital Adherence to Proton Pump Inhibitors Deprescription Flow Chart. [PDF]

Pharmaceuticals (Basel), 2023
The prescriptive appropriateness of Proton Pump Inhibitors (PPIs) in polypharmacy is controversial. PPIs are often overprescribed and the risk of prescribing errors and adverse drug reactions increases for each additional drug added to therapy. Hence, guided deprescription should be considered and easily implementable in ward practice.
Baiardi G, Calvini G, Panarello S, Fioravanti C, Stella M, Martelli A, Antonucci G, Mattioli F.   +7 more
europepmc   +4 more sources