Results 51 to 60 of about 463,262 (274)

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Evaluation of Anti-Depressant Activity of Nasturtium Officinale in Mice [PDF]

open access: yes, 2020
The present study was designed to evaluate the anti-depressant activity of selected EENO using Forced Swimming Test and Tail Suspension Test using the standard drug Fluoxetine (20 mg/kg). In conclusion, EENO showed significant anti depressant activity
Shehsad, P
core  

A multivariate analysis with direct additive and inbreeding depression load effects [PDF]

open access: yesGenetics Selection Evolution, 2019
Abstract Background Inbreeding is caused by mating between related individuals and its most common consequence is inbreeding depression. Several studies have detected heterogeneity in inbreeding depression among founder individuals, and recently a procedure for predicting hidden inbreeding depression loads associated with founders and the Mendelian ...
Varona, Luis   +4 more
openaire   +7 more sources

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

On properties of local additive estimation based on the smooth backfitting estimator. [PDF]

open access: yes, 2008
We study properties of local additive estimation based on the smooth backfitting estimator by Mammen, Linton and Nielsen (1999). The local additive estimator defined as a restricted additive estimator and thus inherits locally properties of additive ...
Seifert, Burkhardt, Park, Juhyun
core   +3 more sources

Additional file 1: of Treatment resistant depression in women with peripartum depression

open access: yes, 2019
Codes used to define depression. (DOCX 13 kb)
Cepeda, M.   +2 more
openaire   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Multivariable meta-regression model four–outcome anti-depressant medication use.

open access: yes, 2019
Multivariable meta-regression model four–outcome anti-depressant medication use.
Peter Bower (52501)   +13 more
core   +1 more source

Water of Increased Ionic Strength on Surface Interactions with Labradorite

open access: yesProceedings
Labradorite is a beautiful and popular mineral known for its iridescent play of colour. It is commonly found in igneous rocks and belongs to the feldspar group of minerals which are common in sulfidic Cu-Ni-PGM ores in South Africa. Labradorite primarily
Malibongwe S. Manono   +3 more
doaj   +1 more source

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