Results 181 to 190 of about 6,188,041 (247)

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source

Research progress on chemical composition, pharmacological effects, clinical applications, and processing of <i>Curcumae Radix</i>. [PDF]

Front Pharmacol
Wang L, Zhou Q, Zhu J, Lu Q, Zhang L, Jin M, Dai Y, Shi D.   +7 more
europepmc   +1 more source

Phonon‐Driven Tetrahedral Tilts Enable Ultralow Bulk Thermal Expansion and Interstitial Oxide‐Ion Migration in Phenacite Solid Electrolytes

Advanced Science, EarlyView.
This work demonstrates a design paradigm of phonon‐driven negative‐thermal‐expansion (NTE) flexible framework that exploits the intrinsic lattice flexibility of NTE frameworks to simultaneously suppress thermal expansion and activate oxide‐ion conduction, offering a promising strategy to mitigate TEC mismatch in solid‐state ionic devices.
Xiaohui Li, Lu liang, Qilong Shi, Xiaoge Wang, Cheng Li, Sihao Deng, Lunhua He, Qiang Li, Kun Lin, Xianran Xing, Xiaojun Kuang   +10 more
wiley   +1 more source

Unlocking Low‐Melting‐Point and High‐Conductivity Molten Salts via High‐Entropy Strategy with Demonstration in Thermal Batteries

Advanced Science, EarlyView.
A high‐entropy strategy is developed to break the trade‐off between low melting point and high ionic conductivity in molten salt electrolytes. By incorporating CsBr and LiF into the LiCl‐LiBr‐KBr system, the quinary LiF‐LiCl‐LiBr‐KBr‐CsBr electrolyte achieves a record‐low melting point of 229.5°C while maintaining a high conductivity of 1.19 S cm−1 at ...
Binchao Shi, Ting Sun, Fushan Yu, Yi Zhang, Gaowu Wang, Ting Quan, Yan‐li Zhu   +6 more
wiley   +1 more source

Safety and Efficacy of Natural and Conventional Psychiatric Treatments: A Comparative Review of Mushroom-Derived Compounds and Medicinal Plants in the Management of Mental Disorders. [PDF]

Molecules
Gawłowska K, Nowakowska KK, Makówka JW, Bajurny W, Góral MP, Bocheńska A, Kopecki SD, Grodzińska WM, Chłopaś-Konowałek A.   +8 more
europepmc   +1 more source

Bond‐Competition‐Driven Enhancement of Surface Basicity and Interfacial Interaction to Boost Photocatalytic Syngas Production

Advanced Science, EarlyView.
A synergetic surface bond competition−hybridization approach was developed to synthesize high‐performance CO2 adsorbents and syngas production photocatalysts via the sulfurization‐driven control of surface basicity and interfacial coupling. The ZnIn2S4−sulfur‐doped MgO/MgAl2O4 nanocomposites showed outstanding photocatalytic efficiency for production ...
Dong Wook Lee, Wenjing Dong, Nam Hee Kwon, Taehoon Kim, In Young Kim, Yun Kyung Jo, Xiaoyan Jin, Ajayan Vinu, Yufei Zhao, Seong‐Ju Hwang   +9 more
wiley   +1 more source

A Monolithic Janus Hydrogel Pressure Sensor for Wearable Motion and Physiological Monitoring

Advanced Science, EarlyView.
This work reports a monolithic Janus hydrogel pressure sensor featuring integrated conductive PEDOT and insulating PEGDA layers. The fabricated device achieves a rapid response time, a wide operating range, and good cyclic durability. The sensor demonstrates robust performance in tracking dynamic human joint motions, offering a scalable strategy for ...
Syed Atif Ali, Zeeshan Alam Ansari, Reynaldo Carlos Kuizon Montalbo, Hailemichael Ayalew, Yu‐Sheng Hsiao, Chih‐Wei Chu, Hsiao‐hua Yu, Hsiung‐Lin Tu   +7 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Metal Ions in Longgu (Fossilized Bone) as a Natural Synergistic Network for Multi-Target Therapy in Psychiatric Disorders. [PDF]

Chem Biodivers
Xiujia S, Hua LZ, Yuanze G, Jing L, Li L, Chao Z, Ganesan K, Chen J.   +7 more
europepmc   +1 more source

Molecular‐Level Pore Engineering for Precise Separation via Active Solvent‐Mediated Interfacial Polymerization

Advanced Science, EarlyView.
We demonstrate that microemulsion solvents can actively template molecular‐level pores within selective layer during interfacial polymerization. By creating localized quasi‐homogeneous polymerization zones, the membrane achieved a 7.1‐fold enhancement in water permeance with increased selectivity.
Feng Li, R. M. G. Rajapakse, Yuxin Mou, Deyin Hou, Min Yang   +4 more
wiley   +1 more source