Results 61 to 70 of about 58,276 (312)

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Factors invoved in onset and recovery from postnatal depression [PDF]

, 2006
Background: A wide variety of psychosocial variables have been implicated in the onset and recovery from postnatal depression. A number of these factors were examined on a representative sample of pregnant Maltese women attending St Luke's Hospital ...
Cox, John, Felice, Ethel, Grech, Victor E., Saliba, Joseph R.   +3 more
core  

Pharmacological Inhibition of FKBP51 Mitigates Early Life Adversity‐Induced Social Deficits in Male Mice

Advanced Science, EarlyView.
Early life adversity triggers persistent social subordination and brain‐wide molecular dysregulation. Pharmacological inhibition of the stress‐mediator FKBP51 during the adversity period prevents these long‐term deficits and restores normative social hierarchy.
Joeri Bordes, Xiuqi Ji, Serena Gasperoni, Choham Sudre‐Chinsky, Amirali Kalbasi, Daniela Harbich, Cornelia Flachskamm, Paula Fontanet, Sowmya Narayan, Manfred Uhr, Christian Namendorf, Camilla Bellone, Alon Chen, Felix Hausch, Juan Pablo Lopez, Mathias V. Schmidt   +15 more
wiley   +1 more source

Depression after Delivery: Risk Factors, Diagnostic and Therapeutic Considerations

The Scientific World Journal, 2007
Postpartum mood disorders can negatively affect women, their offspring, and their families when left untreated. The identification and treatment of postpartum depression remains problematic since health care providers may often not differentiate ...
Debra A. Scrandis, Tehmina M. Sheikh, Robina Niazi, Leonardo H. Tonelli, Teodor T. Postolache   +4 more
doaj   +1 more source

Postpartum depression : epidemiology and theory [PDF]

, 1984
The etiology of postpartum depression was investigated within the framework of Aaron Beck’s cognitive theory of depression and within the framework of previous research on postpartum depression.
Salinger, Margaret Chandler, NC DOCKS at The University of North Carolina at Greensboro   +1 more
core  

Postnatal depression and reproductive success in modern, low-fertility contexts [PDF]

, 2015
Background and objectives: Postnatal depression (PND) presents a puzzling phenomenon to evolutionary anthropologists as it is highly prevalent and yet detrimental to child development and maternal health.
Sarah E. Johns, Myers, Sarah, Johns, Sarah E., Sarah Myers, Burger, Oskar F., Oskar Burger   +5 more
core   +1 more source

Astrocytic FDX1 Contributes to Copper Dyshomeostasis‐associated Synaptic Dysfunction in Depression and Is Modulated by Exercise

Advanced Science, EarlyView.
Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao, Rongji Hui, Zhibo Tang, Tao Feng, Zhihang Hu, Xiaoqing Zhang, Ping Jiang, Hui Zhao, Kwok‐Fai So, Tianyuan Luo, Yanzhou Chang, Lan Yan   +11 more
wiley   +1 more source

Integration of yoga exercise and educational postpartum class reduces cortisol level and depression score in mothers with postpartum depression risk

Zdorovʹe Rebenka
Up to 20 % of mothers worldwide who have recently given birth experience postpartum depression. In Indonesia, the risk of postpartum depression was 57.4 to 65 % according to the Edinburgh Postpartum Depression Scale (EPDS).
Zahra Azizah Danistya, Lilik Herawati, Herdika Ayu Retno Kusumasari, Budi Prasetyo, Sakinah Nuzuliya Izza, Mohd Nahar Azmi Mohamed   +5 more
doaj   +1 more source

Clinical, Behavioral and Neuroradiological Phenotype in an Italian Cohort of Patients With Xia Gibbs Syndrome: A Multicenter Cross‐Sectional Study and Systematic Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous variants in the AHDC1 gene are associated with Xia Gibbs Syndrome (XGS), a genetic disorder with a highly variable phenotype. Cognitive impairment, motor delay, language delay, neonatal hypotonia, and sleep apnea are considered “cardinal” signs of the disease.
Giulia Cinelli, Stefania Della Vecchia, Patrizia Bergonzini, Elisa Caramaschi, Elisabetta Spezia, Claudia Parenti, Simona Filomena Madeo, Laura Lucaccioni, Cavalleri Francesca, Marisa Pugliese, Federico Raviglione, Clara Colonna, Olga Calabrese, Ilaria Stanghellini, Maria Carmen Marongiu, Enrico Biagioni, Anna Rita Ferrari, Roberta Battini, Lorenzo Iughetti   +18 more
wiley   +1 more source

SCREENING OF POST PARTUM DEPRESSION ON THE SEVENTH DAY PUERPERIUM

Indonesian Midwifery and Health Sciences Journal, 2021
Background: Postpartum depression is a psychological disorder during the postpartum period which is more dangerous than the baby blues. Postpartum depression can have a serious impact on the development of the baby as well as the social life of the ...
Wahyu Desiana, Tarsikah Tarsikah
doaj   +1 more source