Results 101 to 110 of about 3,389,680 (314)

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Multimodal prediction of future depressive symptoms in adolescents

BMC Psychiatry
Background Depression rates surge during adolescence. Early identification of youth at increased risk for depression is crucial for timely intervention and, ideally, prevention.
Linshanshan Wang, Ningxuan Zhou, Nigel M. Jaffe, Kristina Pidvirny, Anna O. Tierney, Hadar B. Fisher, Francesca Morfini, Erika E. Forbes, Diego A. Pizzagalli, Tianxi Cai, Christian A. Webb   +10 more
doaj   +1 more source

A powerful intervention: general practitioners' use of sickness certification in depression [PDF]

, 2012
<b>Background</b> Depression is frequently cited as the reason for sickness absence, and it is estimated that sickness certificates are issued in one third of consultations for depression. Previous research has considered GP views of sickness
A Mowlam, B Antony, C Black, C Farrell, C Mallen, C Shiels, CA Chew-Graham, D Cohen, G Wynne-Jones, J Hiscock, J Hisock, J Vahtera, Jill Morrison, JM Corbin, JR Jones, K Ashby, Livanos & Zangelidis, M Balint, M Dollard, M Gabbay, MA Buist-Bowman, Margaret Maxwell, Matt Sutton, MB Gabbay, Michael Smith, P Butterworth, Philip Wilson, S Hussey, S Macdonald, S Nandy, Sara Macdonald, T O’Dowd, U Kelle, Will Whittaker   +33 more
core   +5 more sources

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Prevalence and intensity of depression in mothers of children with beta-thalassemia major in Talghani Hospital of Gorgan, Iran [PDF]

, 2014
Background: Thalassemia is a chronic disease that it leads to psychological and social problems for parents. Mothers are at markedly increased risk of suffering from psychological distress and depression because they usually take on a considerable part ...
Jahazi, A., Karimi, M., Mirbehbahani, N., Salehi, M.   +3 more
core  

Psychoeducational interventions in adolescent depression: A systematic review [PDF]

, 2017
Background: Adolescent depression is common and leads to distress and impairment for individuals/families. Treatment/prevention guidelines stress the need for good information and evidence-based psychosocial interventions.
Bevan Jones, Rhys, Jones, Ian, Simpson, Sharon, Smith, Daniel, Stone, Zoe, Thapar, Ajay, Thapar, Anita   +6 more
core   +3 more sources

Metabolic and Microvascular Risk Factors Associated With Brain Health in Type 1 Diabetes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We examined relationships between metabolic factors, microvascular complications, and brain health in adults with type 1 diabetes. Fifty‐one adults were assessed for metabolic risk factors, microvascular complications, and cognitive function, with a subset completing brain MRI.
Jihyun Park, Emily J. Koubek, Richard Beare, Lynn Ang, Brian C. Callaghan, Rodica Pop‐Busui, Eva L. Feldman, Evan L. Reynolds   +7 more
wiley   +1 more source

Circadian reinforcement therapy in combination with electronic self-monitoring to facilitate a safe post-discharge period of patients with depression by stabilizing sleep: protocol of a randomized controlled trial

BMC Psychiatry, 2019
Background The transition phase from inpatient to outpatient care for patients suffering from Major Depressive Disorder represents a vulnerable period associated with a risk of depression worsening and suicide. Our group has recently found that the sleep-
Signe Dunker Svendsen, Anne Sofie Aggestrup, Lasse Benn Nørregaard, Philip Løventoft, Anne Præstegaard, Konstantin V. Danilenko, Mads Frost, Ulla Knorr, Ida Hageman, Lars Vedel Kessing, Klaus Martiny   +10 more
doaj   +1 more source

Undiagnosed Depression in the Elderly and Healthcare Education [PDF]

, 2016
This descriptive study examined undiagnosed depression in the elderly and how it affects the elderly from retaining healthcare education. It is estimated by 2029, 20% of the United States population will be age 65 and older (Colby & Ortman, 2014 ...
Wynn-Grundy, Nancy J.
core   +1 more source

A Psychometric Properties Evaluation of the Italian Version of the Geriatric Depression Scale [PDF]

, 2018
Objective. The Geriatric Depression Scale (GDS) is an evaluation tool to diagnose older adult's depression. This questionnaire was defined by Yesavage and Brink in 1982; it was designed expressly for the older person and defines his/her degree of ...
Bruni, Valentina, Colucci, Mariele, De Santis, Rita, Galeoto, Giovanni, Sansoni, Julita, Scuccimarri, Michela, Tofani, Marco, Valente, Donatella   +7 more
core   +3 more sources