Results 21 to 30 of about 4,438,444 (356)

The Blurred Line between Physical Ageing and Mental Health in Older Adults: Implications for the Measurement of Depression [PDF]

open access: yes, 2019
Objectives: Depression in older adults is assessed using measures validated in the general adult population. However, such measures may be inappropriate in the elderly due to the similarities between ageing and the symptoms of depression.
Hazell, C.   +5 more
core   +1 more source

Development and validation of a geriatric depression screening scale: a preliminary report.

open access: yesJournal of Psychiatric Research, 1982
A new Geriatric Depression Scale (GDS) designed specifically for rating depression in the elderly was tested for reliability and validity and compared with the Hamilton Rating Scale for Depression (HRS-D) and the Zung Self-Rating Depression Scale (SDS ...
J. Yesavage   +6 more
semanticscholar   +1 more source

A pilot trial of quetiapine, lithium, or placebo added to divalproex sodium for hypomanic or manic episodes in ambulatory adults with bipolar I disorder

open access: yesInternational Journal of Bipolar Disorders, 2022
Background Many patients with bipolar I disorder do not respond to monotherapy treatment with mood-stabilizing medications, and combination regimens are commonly used in both inpatient and outpatient settings for the acute and maintenance treatment of ...
Victoria E. Cosgrove   +5 more
doaj   +1 more source

What contributes to depression in Parkinson's disease? [PDF]

open access: yes, 2001
Background: Depression is a common problem in patients with Parkinson's disease, but its mechanism is poorly understood. It is thought that neurochemical changes contribute to its occurrence, but it is unclear why some patients develop depression and ...
Jahanshahi, M., Quinn, N.P., Schrag, A.
core   +1 more source

Genome-wide transcriptomics of the amygdala reveals similar oligodendrocyte-related responses to acute and chronic alcohol drinking in female mice

open access: yesTranslational Psychiatry, 2022
Repeated excessive alcohol consumption is a risk factor for alcohol use disorder (AUD). Although AUD has been more common in men than women, women develop more severe behavioral and physical impairments. However, relatively few new therapeutics targeting
Sharvari Narendra   +10 more
doaj   +1 more source

Big boys don't cry: Depression and men [PDF]

open access: yes, 2008
Men are a numerical minority group receiving a diagnosis of, and treatment for, depression. However, community surveys of men and of their mental health issues (e.g. suicide and alcoholism) have led some to suggest that many more men have depression than
Branney, P, White, A
core   +1 more source

Familial aggregation of migraine and depression: Insights from a large Australian twin sample [PDF]

open access: yes, 2016
Free to read\ud \ud Objectives: This research examined the familial aggregation of migraine, depression, and their co-occurrence.\ud \ud Methods: Diagnoses of migraine and depression were determined in a sample of 5,319 Australian twins.
Heath, Andrew C   +5 more
core   +3 more sources

Depression [PDF]

open access: yesAnnals of Epidemiology, 2009
This is an invited article on how my career as an epidemiologist studying depression unfolded. The role of the Civil Rights movement in opening the PhD doors to women at Yale began my career. The unfolding of depression studies are described. These studies included a clinical trial of medication and what later was known as interpersonal psychotherapy ...
openaire   +2 more sources

Cardiac Depression Scale: Mokken scaling in heart failure patients [PDF]

open access: yes, 2012
Background: There is a high prevalence of depression in patients with heart failure (HF) that is associated with worsening prognosis. The value of using a reliable and valid instrument to measure depression in this population is therefore essential.
Hare, David L.   +4 more
core   +4 more sources

Efficacy of an internet-based self-management intervention for depression or dysthymia – a study protocol of an RCT using an active control condition

open access: yesBMC Psychiatry, 2019
Background The treatment of major depressive disorder, a highly prevalent disorder associated with pronounced burden, is a large challenge to healthcare systems worldwide.
Caroline Oehler   +6 more
doaj   +1 more source

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