Results 291 to 300 of about 3,423,022 (340)

Association of mold exposure and solid household fuel use with depression and anxiety among older adults in China. [PDF]

Environ Health
Ma X, Zhao H, Wang Y, Hou M, Liu W, Sun M.   +5 more
europepmc   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

The protective role of cognitive reserve in moderating depressive symptomatology in patients with multiple sclerosis. [PDF]

BMC Psychol
Biasi MM, Taurisano P, Manni A, Mangialardi V, Gasparre D, Iaffaldano P, Caputo F, Iaffaldano A, Paolicelli D.   +8 more
europepmc   +1 more source

H2O2‐Activated Serotonin Precursor Probe for Mapping Neuronal Redox Homeostasis Reveals 5‐HT Interactions with Neighboring Proteins Under Oxidative Stress

Advanced Science, EarlyView.
HOP, an innovative ICT‐based fluorescent probe, visualizes H2O2 in stressed neurons while locally releasing serotonin (5‐HT) for real‐time protein interaction mapping. Its unique tandem sensing and labeling strategy reveals 5‐HT's role under oxidative stress, offering a powerful tool for neurophysiological research and therapeutic discovery.
Yani Liu, Jiwen Yuan, Tuanjie Zhang, Xinyi Cai, Meng Xu, Xueao Wang, Rui Wang, Bing Zhang, Hai‐Liang Zhu, Yong Qian   +9 more
wiley   +1 more source

Construction workers' depression, anxiety, stress, and risk factors in China: a cross-sectional study. [PDF]

J Glob Health
Ling Z, Xu Y, Tao M, Zhang B, Zhang M, Zhang Z, DA X, Liu X, Huang L.   +8 more
europepmc   +1 more source

Near Room‐Temperature Ferromagnetic Phase Achieved in 4d Ruthenate via Interfacial Ferrimagnetic Coupling and Octahedral Rotation Engineering

Advanced Science, EarlyView.
Transition metal oxides combining strong spin‐orbit coupling, near‐room‐temperature ferromagnetism, and high conductivity are rare. A Ca0.5Sr0.5RuO3 interfacial phase between LaMnO3 layers has all these features, high Tc, enhanced magnetization, and reduced coercivity.
Mengqin Wang, Qinghua Zhang, Xiao Deng, Jie Zheng, Wenxiao Shi, Yunzhong Chen, Baogen Shen, Yuansha Chen, Tao Zhu, Fengxia Hu, Jirong Sun   +10 more
wiley   +1 more source

Social media addiction as the central mediating variable to explore the mechanism between physical exercise and sleep quality. [PDF]

Sci Rep
Che X, Lu Z, Jin Y.
europepmc   +1 more source

Clinical Features, Molecular Biology, and the Metastatic Microenvironment in Lung Cancer Brain Metastases: Implications for Treatment Decisions

Advanced Science, EarlyView.
Brain metastases (BM) from lung cancer are aggressive with poor prognosis. This review covers clinical features, diagnosis, early metastasis, and multi‐omics‐elucidated mechanisms, especially the tumor microenvironment of lung cancer with BM. It also discusses preclinical models, signaling pathways, and emerging therapies.
Yixiang Zhu, Danming He, Zan Hou, Mei Lan, Ye Zhang, Qifeng Wang   +5 more
wiley   +1 more source

Predictors and Correlates of Depression and Anxiety Symptom Trajectories in a Large Digital Mental Health Provider: Retrospective Analysis of Data From Rula Health.

J Med Internet Res
McAlister KL, Baez L, Newton D, Seiniger S, Pearlman A, Woodhouse A, Huberty J.   +6 more
europepmc   +1 more source

Problematic Smartphone Use Is Associated With Current and Previous Major Depressive Disorder. [PDF]

Psychiatry Investig
Seong SJ, Hong JP, Hahm BJ, Chang SM, Kim BS, Lee DW, Cho SJ, Park JI, Park JE, Jeon HJ.   +9 more
europepmc   +1 more source