Results 231 to 240 of about 354,940 (340)

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun   +10 more
wiley   +1 more source

Flow Near Hemispherical Depressions

open access: yesJournal of the Mechanical Behavior of Materials, 2000
Kaplanski, Felix   +3 more
doaj   +1 more source

Electroactive Electrospun Nanofibrous Scaffolds: Innovative Approaches for Improved Skin Wound Healing

open access: yesAdvanced Science, EarlyView.
This review explores the potential of electroactive electrospun nanofibrous (EEN) scaffolds for enhanced skin wound healing. It discusses how a variety of electroactive materials can be prepared into EEN scaffolds via electrospinning technology, and their applications in various wound types. The review provides insights into the future perspectives for
Yang Zhang   +10 more
wiley   +1 more source

Depression

open access: yesRevue LISA / LISA e-journal, 2020
openaire   +2 more sources

The Lung Microbiome Modulates Pain‐Like Behavior Via the Lung–Brain Axis in a Nitroglycerin‐Induced Chronic Migraine Mouse Model

open access: yesAdvanced Science, EarlyView.
Intratracheal neomycin alters pulmonary microbiota, activating the vagus nerve via lung brain‐derived neurotrophic factor/tropomyosin receptor kinase B (BDNF/TrkB) pathway, further projecting to nucleus of solitary tract (NTS), then dorsal raphe nucleus (DRN), where activated serotoninergic neurons increase brain serotonin, alleviating migraine.
Biying Liu   +7 more
wiley   +1 more source

Shark Fin Sign on a 12-Lead ECG. [PDF]

open access: yesDtsch Arztebl Int
Macherey-Meyer S, Terporten J, Adler C.
europepmc   +1 more source

S‐ketamine Alleviates Neuroinflammation and Attenuates Lipopolysaccharide‐Induced Depression Via Targeting SIRT2

open access: yesAdvanced Science, EarlyView.
S‐ketamine binds directly to SIRT2, facilitating its interaction with NF‐κB p65. This interaction reduces the acetylation of NF‐κB p65 and inhibits its activation, thereby exerting anti‐inflammatory and antidepressant effects. Created by BioRender.
Cong Lin   +7 more
wiley   +1 more source

Colchicine: A Dual Therapeutic Target for Trichinellosis. [PDF]

open access: yesActa Parasitol
Hamed EFA   +4 more
europepmc   +1 more source

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