Results 21 to 30 of about 496,967 (242)

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo, Kilian Hett, Amy Cooper, Amy E. Brown, Jessica Iregui, Manus J. Donahue, M. Erik Landman, Italo Biaggioni, Margaret Bradbury, Cynthia Wong, David Stamler, Daniel O. Claassen   +11 more
wiley   +1 more source

The Stellar and Gaseous Contents of the Orion Dwarf Galaxy [PDF]

, 2010
We present new KPNO 0.9-m optical and VLA HI spectral line observations of the Orion dwarf galaxy. This nearby (D ~ 5.4 Mpc), intermediate-mass (M_dyn = 1.1x10^10 Solar masses) dwarf displays a wealth of structure in its neutral ISM, including three ...
Arthur Sugden, Bell, Brinks, Cannon, Cannon, Caplan, Cox, Hans Most, Hunter, Jacob Weindling, Jillian Scudder, John J. Salzer, John M. Cannon, Kaitlin Haugland, Karachentsev, Kennicutt, Kim, Korey Haynes, Lee, Lee, McQuinn, Oh, Ott, Puche, Rhode, Schlegel, Skillman, Springob, Sánchez-Salcedo, Vaduvescu, Walter, Walter, Walter, Walter, Weisz, Weisz   +35 more
core   +1 more source

BCS1L‐Associated Disease: 5′‐UTR Variant Shifts the Phenotype Towards Axonal Neuropathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives To investigate the consequences of a pathogenic missense variant (c.838C>T; p.L280F) and a 5′‐UTR regulatory variant (c.‐122G>T) in BCS1L on disease pathogenesis and to understand how regulatory variants influence disease severity and clinical presentation.
Rotem Orbach, Nunziata Maio, Russell J. Butterfield, A. Reghan Foley, Sarah Silverstein, Yan Li, Katherine Chao, Tanya J. Lehky, Abigail Potticary, Tracey A. Rouault, Sandra Donkervoort, Carsten G. Bönnemann   +11 more
wiley   +1 more source

Maars to calderas. End-members on a spectrum of explosive volcanic depressions [PDF]

, 2015
We discuss maar-diatremes and calderas as end-members on a spectrum of negative volcanic landforms (depressions) produced by explosive eruptions (note—we focus on calderas formed during explosive eruptions, recognizing that some caldera types are not ...
Palladino, Danilo Mauro, Sottili, Gianluca, Taddeucci, J., Valentine, G. A.   +3 more
core   +1 more source

Correlation Between Irisin and Cognitive Functions in Alzheimer Dementia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The myokine irisin, a recent positive mediator of exercise in the brain, shows neuroprotective functions against Alzheimer's disease (AD). The association between irisin and cognition has never been explored in a biologically defined cohort of patients.
Patrizia Pignataro, Manuela Dicarlo, Chiara Zecca, Daniele Urso, Maria Teresa Dell'Abate, Davide Vilella, Francesco Borlizzi, Roberta Zerlotin, Angela Oranger, Graziana Colaianni, Silvia Colucci, Maria Grano, Giancarlo Logroscino   +12 more
wiley   +1 more source

Sea Beam Survey of an Active Strike-Slip Fault: The San Clemente Fault in the California Continental Borderland [PDF]

, 1989
The San Clemente fault, located in the California Continental Borderland, is an active, northwest trending, right-lateral, wrench fault. Sea Beam data are used to map the major tectonic landforms associated with active submarine faulting in detail ...
de Moustier, Christian, Legg, Mark R, Luyendyk, Bruce P, Mammerickx, Jacqueline, Tyce, Robert C.   +4 more
core   +2 more sources

Timing and Predictive Value of Clinical Conditions Preceding Multiple Sclerosis in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Multiple sclerosis (MS) patients often experience a higher incidence of clinical conditions before diagnosis, suggesting a prodromal phase. However, their predictive value and temporal trajectories remain underexplored. We investigated these aspects using the large UK Biobank's population‐based cohort, which provided clinical ...
Andrea Nova, Teresa Fazia, Giovanni Di Caprio, Davide Gentilini, Luisa Bernardinelli, Roberto Bergamaschi   +5 more
wiley   +1 more source

Chandra and XMM-Newton X-ray observations of AWM 7 - I: Investigating X-ray surface brightness fluctuations

, 2011
We investigate the levels of small scale structure in surface brightness images of the core of the X-ray bright cool-core galaxy cluster AWM 7. After subtraction of a model of the smooth cluster emission, we find a number of approximately radial surface ...
A. C. Fabian, Armstrong, Ascasibar, Beers, Blanton, Brüggen, Cavagnolo, Churazov, Churazov, Churazov, Churazov, Dutta, Edge, Fabian, Fabian, Forman, Furusho, Graham, Hatch, Heinz, J. S. Sanders, Kim, Koranyi, Koranyi, Kowal, Kuntz, Kunz, Lau, Lesieur, McNamara, Neumann, Ossenkopf, Peres, Sanders, Sanders, Sanders, Sanders, Sanders, Sanders, Sanders, Sato, Schuecker, Smith, Stanimirovic, Stutzki, Vazza, Vazza, Werner   +47 more
core   +1 more source

Clinical Characteristics of Parkinsonism in HTLV‐1‐Associated Myelopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Human T‐lymphotropic virus type 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is the classic neurological manifestation of HTLV‐1 infection; however, this virus has also been associated with other neurological disorders. Concurrent parkinsonism is relatively rare and presents diagnostic challenges.
Mika Dozono, Satoshi Nozuma, Shota Hirakata, Takashi Yoshida, Daisuke Kodama, Masakazu Tanaka, Eiji Matsuura, Ryuji Kubota, Hiroshi Takashima   +8 more
wiley   +1 more source

Sampietrini stone pavements: Distress analysis using pavement condition index method [PDF]

, 2017
In several Italian cities, it is possible to find historical pavements such as the Sampietrini pavements, which are mainly located in the center of the city of Rome.
Galoni, Andrea, Loprencipe, Giuseppe, Zoccali, Pablo   +2 more
core   +1 more source