Results 51 to 60 of about 520,290 (337)

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

open access: yesFEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui   +3 more
wiley   +1 more source

Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations

open access: yesFEBS Open Bio, EarlyView.
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro   +8 more
wiley   +1 more source

Saddle Position-Based Method for Extraction of Depressions in Fengcong Areas by Using Digital Elevation Models

open access: yesISPRS International Journal of Geo-Information, 2018
A karst depression is an important sign of the development stage of karst landforms. The morphological characteristics of depressions can help reflect the development and evolution process of such landforms.
Xianwu Yang   +3 more
doaj   +1 more source

Chandra and XMM-Newton X-ray observations of AWM 7 - I: Investigating X-ray surface brightness fluctuations

open access: yes, 2011
We investigate the levels of small scale structure in surface brightness images of the core of the X-ray bright cool-core galaxy cluster AWM 7. After subtraction of a model of the smooth cluster emission, we find a number of approximately radial surface ...
A. C. Fabian   +47 more
core   +1 more source

The Stellar and Gaseous Contents of the Orion Dwarf Galaxy [PDF]

open access: yes, 2010
We present new KPNO 0.9-m optical and VLA HI spectral line observations of the Orion dwarf galaxy. This nearby (D ~ 5.4 Mpc), intermediate-mass (M_dyn = 1.1x10^10 Solar masses) dwarf displays a wealth of structure in its neutral ISM, including three ...
Arthur Sugden   +35 more
core   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

open access: yesFEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Assessment of climatic extremes over Northeast and West Coast regions of India

open access: yesGeoadria, 2015
Extreme weather and climate variability have become a subject of big concern worldwide. In response, efforts have been made to evaluate the trends in climatic parameters in two geographical regions of India – Northeast (NER) and West coast region (WCR ...
Tongdi Jamir, G. Krishna Kumar
doaj  

SALINITY OF SOILS OF INTERMOUNTAIN DEPRESSIONS IN THE DESERTS OF THE ZALTAI GOBI OF MONGOLIA

open access: yesБюллетень Почвенного института им. В.В. Докучаева, 2010
Intermountain depressions (depressions) are a characteristic feature of Zaaltai Gobi landscapes in Mongolia. There are three types of depressions, each of which is characterized by peculiarities of soil structure and specificity of soil salinity.
E. Pankova
doaj   +1 more source

Research progress on the metabolic transformation of Shenling Baizhu San under the influence of the gut microbiota

open access: yesAdvanced Chinese Medicine, EarlyView.
Abstract The gut microbiota plays a pivotal role in maintaining host metabolic homeostasis and overall physiological functions. Shenling Baizhu San (SLBZS), a time‐honored classical prescription for tonifying Qi, strengthening the spleen, removing dampness, and arresting diarrhea, has shown broad clinical efficacy in digestive disorders.
Jinlan Di, Xiaochun Zhang
wiley   +1 more source

Caves, sinkholes, and fractures in the eogenetic karst of Florida, a GIS-based spatial analysis

open access: yesActa Carsologica, 2022
The correlation between surface and subsurface karst development was explored by comparing the directionality and spatial distribution of karstic depressions around twenty-two select caves in the eogenetic karst of Florida.
Can Denizman
doaj   +1 more source

Home - About - Disclaimer - Privacy