Results 171 to 180 of about 496,245 (299)

Esketamine in a Patient With Major Depressive Disorder and Polysubstance Use: A Case Report. [PDF]

Cureus
Ali A, Ahmed N, Varghese S.
europepmc   +1 more source

Nortriptyline Inhibits Lysosomal Exocytosis‐Mediated SASP During Gastric Cancer Progression via Targeting HOXA1‐PITX2 Phase Separation

Advanced Science, EarlyView.
This study identifies that HOXA1 facilitates transcriptional activity of PITX2 in liquid condensates, resulting in up‐regulation of MCOLN1 and RAB3A followed by lysosomal exocytosis of LGALS1 and IGFBP7 from senescent cells, thus activating AKT signaling and EMT.
Yi Zhou, Chunhui Yang, Xinyue Li, Xiaojing Wang, Wanju Jiao, Xiaolin Wang, Jiaying Qu, Bosen Zhao, Shunchen Zhou, Qiangsong Tong, Liduan Zheng   +10 more
wiley   +1 more source

The association between white matter hyperintensities and suicide attempts in affective disorders: a systematic review and meta-analysis. [PDF]

Transl Psychiatry
Torino G, Maggioni E, Lengvenyte A, Brambilla P, Delvecchio G.   +4 more
europepmc   +1 more source

Symmetry Breaking in Chemical Systems: Engineering Complexity Through Self‐Organization and Marangoni Flows

Advanced Science, EarlyView.
We show that solutal Marangoni flows in thin films climbing the outer surfaces of hydrophilic obstacles break circular Belousov‐Zhabotinsky waves into striking flower‐like patterns. Evaporation‐driven surface‐tension gradients, coupled with gravity, trigger the instability; above a threshold, petal number scales linearly with obstacle diameter ...
Sangram Gore, Binaya R. Paudyal, Duarte Rocha, Mohamed Ali, Nader Masmoudi, Albert J. Bae, Christian Diddens, Detlef Lohse, Oliver Steinbock, Azam Gholami   +9 more
wiley   +1 more source

Effect of Visceral Adipose Tissue on Major Depressive Disorder: A Mendelian Randomisation Research. [PDF]

Actas Esp Psiquiatr
Li X, Zhou X, Li Y, Lei C.
europepmc   +1 more source

Microglial Rack1 Deficiency Alleviates Alzheimer's Disease Pathology through Enhancing IGF1‐Mediated Astrocytic Phagocytosis

Advanced Science, EarlyView.
Alzheimer's disease (AD) is the most common neurodegenerative disorder. This study demonstrates that microglial Rack1 deficiency decreased Aβ deposition and neuroinflammation and ameliorated cognitive impairments in AD model mice by enhancing IGF1‐mediated astrocytic phagocytosis.
Jingdan Zhang, Yanling He, Pin Yang, Hengchang Zhang, Yueyang Tong, Lingling Jiang, Zehan Li, Meichen Yan, Xiaoheng Li, Qinghu Yang, Jing Yang, Zengqiang Yuan, Jiyan Zhang, Jinbo Cheng   +13 more
wiley   +1 more source

Time trend and geographical distribution of major depressive disorder in Iran, 1990 to 2021: results from the Global Burden of Disease Study. [PDF]

BMJ Open
Taheri Soodejani M, Shakeri Shamsi F.
europepmc   +1 more source

Micro/Nanorobots for Combating Brain Disorders: Challenges, Advances, and Perspectives

Advanced Science, EarlyView.
Micro/nanorobots (MNRs) offer a transformative approach for precision therapy in brain disorders. By overcoming biological barriers and enabling controlled propulsion, targeted delivery, and real‐time imaging/tracking, MNRs pave the way toward effective, minimally invasive treatments. This review outlines the interplay between brain disease challenges,
Qi Zhang, Dong Sun
wiley   +1 more source

Rheumatoid arthitis and major depressive disorder [PDF]

MedUNAB, 2003
Juan Guillermo Lozano de Castro, Boris Miguel Hernández Lizarazo   +1 more
doaj  

Designing Memristive Materials for Artificial Dynamic Intelligence

Advanced Intelligent Discovery, EarlyView.
Key characteristics required of memristors for realizing next‐generation computing, along with modeling approaches employed to analyze their underlying mechanisms. These modeling techniques span from the atomic scale to the array scale and cover temporal scales ranging from picoseconds to microseconds. Hardware architectures inspired by neural networks
Youngmin Kim, Ho Won Jang
wiley   +1 more source