Results 201 to 210 of about 371,357 (236)

Pharmacokinetic Prediction and Cytotoxicity of New Quercetin Derivatives

Chemistry &Biodiversity, EarlyView.
ABSTRACT Quercetin (QUE) possesses various pharmacological properties; however, its low bioavailability and solubility hinder its beneficial effects. Enzymatic glycosylation has been explored to improve these aspects. In the present study, we used a sucrose phosphorylase variant to catalyze the regioselective transglucosylation of QUE, predicted the ...
Michele Goulart dos Santos, Marie Demonceaux, Lucia Emanueli Schimith, Marine Goux, Claude Solleux, Ana Luiza Muccillo‐Baisch, Bruno Dutra Arbo, Corinne Andre‐Miral, Mariana Appel Hort   +8 more
wiley   +1 more source

Depressive Symptoms and Risk Factors During the COVID-19 Pandemic Among People with/Without Mental Disorders. [PDF]

Healthcare (Basel)
Fukase Y, Ichikura K, Inaoka H, Tagaya H.   +3 more
europepmc   +1 more source

Stressful Life Events and Neuroticism among Chinese Women with Recurrent Major Depressive Disorder. [PDF]

Actas Esp Psiquiatr
Chu F, Wang C, Tao S, Gao J, Zhu X, Tao D, Chen B, Tao M.   +7 more
europepmc   +1 more source

A longitudinal analysis of the relationship between emotional symptoms and cognitive function in patients with major depressive disorder. [PDF]

Psychol Med
Zhou J, Xu J, Feng Z, Liu R, Xiao L, Li R, Li X, Zhang X, Liu J, Feng Y, Zhou J, Wang G.   +11 more
europepmc   +1 more source

The interrelationship of depression, stigma, and suicide risk among patients with bipolar disorder and their caregivers: a six-month follow-up study. [PDF]

Int J Bipolar Disord
Lin CC, Lee Y, Chiu NM, Lin PY, Huang YC, Hung CF, Wang LJ.   +6 more
europepmc   +1 more source

Association Between Body Mass Index and Comorbid Anxiety in First-Episode and Drug Naïve Patients With Major Depressive Disorder. [PDF]

Depress Anxiety
Liu S, Huang Y, Liu A, Li X, Fu Y, Wang W, Wen Y, Jiang T, Zhang X.   +8 more
europepmc   +1 more source

Degree centrality values in the left calcarine as a potential imaging biomarker for anxious major depressive disorder. [PDF]

World J Psychiatry
Gao YJ, Meng LL, Lu ZY, Li XY, Luo RQ, Lin H, Pan ZM, Xu BH, Huang QK, Xiao ZG, Li TT, Yin E, Wei N, Liu C, Lin H.   +14 more
europepmc   +1 more source

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Major depressive disorder

Nature Reviews Disease Primers, 2023
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and physical and cognitive symptoms. People with MDD can have reduced quality of life owing to the disorder itself as well as related medical comorbidities, social factors, and ...
Wolfgang Marx, Brenda W. J. H. Penninx, Marco Solmi, Toshi A. Furukawa, Joseph Firth, Andre F. Carvalho, Michael Berk   +6 more
openaire   +6 more sources

Major Depressive Disorder

New England Journal of Medicine, 2008
Depression is related to the normal emotions of sadness and bereavement, but it does not remit when the external cause of these emotions dissipates, and it is disproportionate to their cause. Classic severe states of depression often have no external precipitating cause.
Saini A, Ardine M, BERRUTI, Alfredo
  +10 more sources