Results 321 to 330 of about 786,893 (341)

The genetics of major depressive disorder

Current Psychiatry Reports, 2000
There is consistent evidence that major depression is familial and population-based twin studies as well as hospital register-based twin studies find substantial heritability. However, there is also a large proportion of variation in liability left to be explained by nongenetic factors.
Janette Moore, Gin S Malhi, Peter McGuffin   +2 more
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Major depression and personality disorder

Journal of Affective Disorders, 1991
The authors examined an interview and paper-and-pencil assessment of the DSM-III personality disorders (PDs) in depressed inpatients, and depressed relatives of psychiatric patients and never-ill controls who had a lifetime history of major depression. The rates of PDs according to the Structured Interview for DSM-III Personality Disorders (SIDP) were ...
Caryn Corenthal, Mark Zimmerman, D Stangl, William Coryell, Bruce Pfohl   +4 more
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Subtyping Major Depressive Disorder

Psychotherapy and Psychosomatics, 2010
during their lifetime in epidemiological studies using current criteria [4] . It is unlikely that a syndrome as polymorphic and widely diagnosed as major depressive disorder (MDD) will reflect a single process. Attempts to delineate different forms of depression by statistically analyzing the symptomatology of large samples of patients without taking ...
Pesach Lichtenberg, Robert H. Belmaker
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Major Depressive Disorder in a Preschooler

Journal of the American Academy of Child Psychiatry, 1985
The history and evaluation of a preschool child who meets criteria for major depressive disorder are reported. In addition to describing the multifaceted workup required, the authors acknowledge the developmental issues which makes the diagnosis of depression difficult in this age group.
Gabrielle A. Carlson, Javad H. Kashani
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Hypersomnia in major depressive disorders

Journal of Affective Disorders, 1984
Hypersomnia was experienced by 17 of 102 patients with major depressive disorder. Comparisons between hypersomnic and non-hypersomnic depressives demonstrated significant associations between hypersomnia and increased appetite, weight gain, agitation, headaches, depression in a first-degree relative, and earlier age of illness onset.
Dan M Mungas, Michael J. Garvey, Gary D. Tollefson   +2 more
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Major Depressive Disorder

2014
Depression affects about 121 million people worldwide and is characterized by episodes of affective, somatic, cognitive, and motivational symptoms generally expressed by loss of interest and pleasure with increasing functional impairment, morbidity, and mortality.
Stefano Baroni, Liliana Dell'Osso, Grazia Rutigliano, Donatella Marazziti   +3 more
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Migraine symptomatology and major depressive disorder

Cephalalgia, 2010
Introduction and objective: Migraine and major depressive disorder (MDD) frequently co-occur, but it is unclear whether depression is associated with a specific subtype of migraine. The objective of this study was to investigate whether migraine is qualitatively different in MDD patients ( N = 1816) and non-depressed controls ( N = 3428).
Dale R. Nyholt, Dorret I. Boomsma, Johannes H. Smit, Lannie Ligthart, Gonneke Willemsen, Marijn A. Distel, Eco J. C. de Geus, Brenda W.J.H. Penninx, Brenda W.J.H. Penninx, Brenda W.J.H. Penninx   +9 more
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Major Depressive Disorder

Abstract This chapter looks at the section on Major Depressive Disorder in the Anxiety and Related Disorders Interview Schedule for DSM-5, Child Version: Parent Interview Schedule (PIS). If the parent responds “Yes” to Question 1a and “No” to Question 1b (parent reports past depression but denies current episode), the interviewer should ...
Anne Marie Albano, Wendy K. Silverman
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MicroRNAs in Major Depressive Disorder

2019
Major depressive disorder (MDD) is a severe and chronic psychiatric disorder with a high prevalence in the population. Although our understanding of its pathophysiological mechanisms has significantly increased over the years, available treatments still present several limitations and are not effective to all MDD patients.
Deborah Benevenuto, Wei Zhang, João Quevedo, Gabriel Rodrigo Fries   +3 more
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Epigenetics of Major Depressive Disorder

2020
Epigenetic modifications can alter gene expression through mechanisms that are heritable, but do not involve direct changes in the nucleotide sequence of the genome. Recent findings have suggested that epigenetic modifications are associated with several psychiatric disorders.
Wang K. Z., Dada O. O., Bani-Fatemi A., Tasmim S., Monda M., Graff A., De Luca V.   +6 more
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