Results 61 to 70 of about 786,893 (341)

Prevalence and correlates of major depressive disorder: a systematic review

Revista Brasileira de Psiquiatria, 2020
Objectives: Major depressive disorder (MDD) is one of the most disabling mental illnesses and it has a significant impact on society. This review aims to provide updated scientific evidence about the epidemiology of MDD.
L. Gutiérrez-Rojas, A. Porras-Segovia, Henry Dunne, N. Andrade-González, J. Cervilla   +4 more
semanticscholar   +1 more source

Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohort [PDF]

, 2016
BACKGROUND: Late-life sub-threshold depressive symptoms (i.e. depressive symptoms that do not meet the criteria for a diagnosis of major depressive disorder) are associated with impaired physical health and function, and increased risk of major ...
Allan, CL, Ebmeier, KP, Filippini, N, Kivimaki, M, Mackay, CE, Mahmood, A, Sexton, CE, Shipley, MJ, Singh-Manoux, A, Topiwala, A, Zsoldos, E   +10 more
core   +4 more sources

Major depressive disorder: hypothesis, mechanism, prevention and treatment

Signal Transduction and Targeted Therapy
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually, resulting in greater economic and social burdens. Moreover, the pathological mechanisms of MDD and the mechanisms underlying the effects of pharmacological treatments for
Lulu Cui, Shu Li, Siman Wang, Xiafang Wu, Yingyu Liu, Weiyang Yu, Yijun Wang, Yong Tang, Maosheng Xia, Baoman Li   +9 more
semanticscholar   +1 more source

Exploring Risk Factors for Major Depressive Disorder for Female Patients Aged 18 or Older Living in Ocean County, New Jersey [PDF]

, 2023
Background: The incidence and prevalence of major depressive disorder has been increasing worldwide, in the United States of America, and on a local level.
Mack, James
core   +1 more source

Generalized Anxiety Disorder, Major Depressive Disorder, and Their Comorbidity as Predictors of All-Cause and Cardiovascular Mortality: The Vietnam Experience Study

Psychosomatic Medicine, 2009
Objective: To examine whether the 1-year prevalence of major depressive disorder (MDD), generalized anxiety disorder (GAD), and their comorbidity were associated with subsequent all-cause and cardiovascular disease (CVD) mortality during 15 years in ...
Anna C. Phillips, G. Batty, C. Gale, I. Deary, D. Osborn, K. MacIntyre, D. Carroll   +6 more
semanticscholar   +1 more source

Validating a functional near-infrared spectroscopy diagnostic paradigm for Major Depressive Disorder

Scientific Reports, 2020
Reduced haemodynamic response in the frontotemporal cortices of patients with major depressive disorder (MDD) has been demonstrated using functional near-infrared spectroscopy (fNIRS).
S. F. Husain, Rongjun Yu, T. Tang, W. Tam, B. Tran, Travis T C Quek, Shi-Hui Hwang, Cheryl W. L. Chang, Cyrus S. H. Ho, R. Ho   +9 more
semanticscholar   +1 more source

Skin calcium deposits in primary familial brain calcification: A novel potential biomarker

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective Primary Familial Brain Calcification (PFBC) is a rare neurodegenerative disorder characterized by small vessel calcifications in the basal ganglia. PFBC is caused by pathogenic variants in different genes and its physiopathology is still largely unknown. Skin vascular calcifications have been detected in single PFBC cases, suggesting
Aron Emmi, Giulia Bonato, Aleksandar Tushevski, Cinzia Bertolin, Francesco Cavallieri, Andrea Porzionato, Angelo Antonini, Leonardo Salviati, Miryam Carecchio   +8 more
wiley   +1 more source

Tobacco smoking as a risk factor for major depressive disorder : a population-based study

, 2008
Background : Smoking is disproportionately prevalent among people with psychiatric illness. Aims : To investigate smoking as a risk factor for major depressive disorder. Method : A population-based sample of women was studied using case–control and
Berk, Michael, Henry, Margaret J., Jacka, Felice N., Kotowicz, Mark A., Ng, Felicity, Nicholson, Geoffrey C., Pasco, Julie A., Williams, Lana J.   +7 more
core   +1 more source

The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls [PDF]

, 2020
Background: Mood disorders (including major depressive disorder and bipolar disorder) affect 10% to 20% of the population. They range from brief, mild episodes to severe, incapacitating conditions that markedly impact lives.
Bipolar Disorder Working Group of the Psychiatric Genomics Conso, Bryois, J, Coleman, JRI, Gaspar, HA   +3 more
core  

Cortical abnormalities in adults and adolescents with major depression based on brain scans from 20 cohorts worldwide in the ENIGMA Major Depressive Disorder Working Group

Molecular Psychiatry, 2016
The neuro-anatomical substrates of major depressive disorder (MDD) are still not well understood, despite many neuroimaging studies over the past few decades.
L. Schmaal, D. Hibar, P. Sämann, G. Hall, B. Baune, N. Jahanshad, J. Cheung, T. V. Erp, D. Bos, M. Ikram, M. Vernooij, W. Niessen, W. Niessen, H. Tiemeier, H. Tiemeier, A. Hofman, K. Wittfeld, H. Grabe, Deborah Janowitz, R. Bülow, M. Selonke, H. Völzke, D. Grotegerd, U. Dannlowski, U. Dannlowski, V. Arolt, N. Opel, W. Heindel, H. Kugel, D. Hoehn, M. Czisch, B. Couvy-Duchesne, B. Couvy-Duchesne, M. Rentería, Lachlan T. Strike, M. Wright, Natalie T. Mills, Natalie T. Mills, G. Zubicaray, K. Mcmahon, S. Medland, N. Martin, N. Gillespie, R. Goya-Maldonado, O. Gruber, B. Krämer, S. Hatton, J. Lagopoulos, I. Hickie, T. Frodl, T. Frodl, A. Carballedo, Eva-Maria Frey, L. V. Velzen, B. Penninx, M. V. Tol, N. Wee, C. Davey, B. Harrison, B. Mwangi, B. Cao, J. Soares, I. Veer, Henrik Walter, D. Schoepf, B. Zurowski, C. Konrad, E. Schramm, C. Normann, K. Schnell, M. Sacchet, I. Gotlib, G. MacQueen, B. Godlewska, T. Nickson, A. McIntosh, A. McIntosh, M. Papmeyer, M. Papmeyer, H. Whalley, J. Hall, J. Hall, J. Sussmann, Meng Li, M. Walter, L. Aftanas, I. Brack, N. Bokhan, N. Bokhan, N. Bokhan, P. Thompson, D. Veltman   +91 more
semanticscholar   +1 more source