Results 101 to 110 of about 3,696,874 (383)

The association between aids related stigma and major depressive disorder among HIV-positive individuals in Uganda. [PDF]

PLoS ONE, 2012
BackgroundMajor depressive disorder in people living with HIV/AIDS (PLWHA) is common and may be associated with a number of factors, including AIDS-related stigma, decreased CD4 levels, increased opportunistic infections and sociodemographic variables ...
Dickens Akena, Seggane Musisi, John Joska, Dan J Stein   +3 more
doaj   +1 more source

Meta-analysis of reward processing in major depressive disorder reveals distinct abnormalities within the reward circuit

bioRxiv, 2018
Many neuroimaging studies have investigated reward processing dysfunction in major depressive disorder. These studies have led to the common idea that major depressive disorder is associated with blunted responses within the reward circuit, particularly ...
Tommy H. Ng, L. Alloy, D. Smith
semanticscholar   +1 more source

Childhood depressive disorders. [PDF]

Danish medical journal, 2016
Major depressive disorder (MDD) is a frequent and painful mental disorder considered among the five leading causes of disability in Western countries by the World Health Organization. MDD occurs at all ages, but childhood onset MDD has a more severe course with longer depressive episodes, more suicidality, and more frequent hospitalization, than later ...
openaire   +3 more sources

Is Depression an Inflammatory Disorder? [PDF]

Current Psychiatry Reports, 2011
Studies consistently report that groups of individuals with major depressive disorder (MDD) demonstrate increased levels of a variety of peripheral inflammatory biomarkers when compared with groups of nondepressed individuals. These findings are often interpreted as meaning that MDD, even in medically healthy individuals, may be an inflammatory ...
Andrew H. Miller, Charles L. Raison
openaire   +3 more sources

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source

Risk of Vertebral Fracture in Patients Diagnosed with a Depressive Disorder: A Nationwide Population-Based Cohort Study

Clinics
OBJECTIVE: Previous studies have reported that depression may play a crucial role in the occurrence of vertebral fractures. However, a clear correlation between depressive disorders and osteoporotic fractures has not been established.
Shyh-Chyang Lee, Li-Yu Hu, Min-Wei Huang, Cheng-Che Shen, Wei-Lun Huang, Ti Lu, Chiao-Lin Hsu, Chih-Chuan Pan   +7 more
doaj   +1 more source

Case report of anti-N-methyl-D-aspartate receptor encephalitis in a middle-aged woman with a long history of major depressive disorder

BMC Psychiatry, 2017
Background Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis is an autoimmune disease involving antibodies against the NR1 subunits of NMDARs. The disease shows variable clinical presentation, and involves new-onset acute psychotic symptoms, making
Xia Rong, Zhenzhen Xiong, Bingrong Cao, Juan Chen, Mingli Li, Zhe Li   +5 more
doaj   +1 more source

Real-world assessment of treatment inertia in the management of patients treated for major depressive disorder in the USA

Journal of Comparative Effectiveness Research, 2023
Aim: Major depressive disorder (MDD) is a debilitating illness in which depressive symptoms may persist after treatment. Treatment inertia is the continued use of the same pharmacotherapy regimen when treatment goals are not met.
John J Sheehan, Chris LaVallee, Keshia Maughn, Santosh Balakrishnan, Jacqueline A Pesa, Kruti Joshi, Craig Nelson   +6 more
doaj   +1 more source

Sub-threshold depressive symptoms and brain structure: A magnetic resonance imaging study within the Whitehall II cohort [PDF]

, 2016
BACKGROUND: Late-life sub-threshold depressive symptoms (i.e. depressive symptoms that do not meet the criteria for a diagnosis of major depressive disorder) are associated with impaired physical health and function, and increased risk of major ...
Allan, CL, Ebmeier, KP, Filippini, N, Kivimaki, M, Mackay, CE, Mahmood, A, Sexton, CE, Shipley, MJ, Singh-Manoux, A, Topiwala, A, Zsoldos, E   +10 more
core  

Genetic Modifiers of Parkinson's Disease: A Case–Control Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik, Michael V. Holmes, Pierre Fontanillas, Giulietta M. Riboldi, Ruth B. Schneider, Jingchunzi Shi, Anna Guan, Susana Tat, Steven Micheletti, Keaton Stagaman, Josh Gottesman, David A. Hinds, Joyce Y. Tung, 23andMe Research Team, Stella Aslibekyan, Lucy Norcliffe‐Kaufmann   +15 more
wiley   +1 more source