Mirtazapine and Trazodone Efficacy on Major Depressive Disorder (MDD) is Moderated by Patients’ Age and Sex: A Randomized, Controlled Trial [PDF]
Maja Vilibić +4 more
openalex +1 more source
Advancing treatment paradigms: the role of psilocybin in managing major depressive disorder. [PDF]
Rasheed S, Arif R, Raza AA, Samadi A.
europepmc +1 more source
Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang +12 more
wiley +1 more source
Clinical features of eating disorders in anxiety-depressive disorders. [PDF]
Вікторія Огоренко +1 more
openalex +1 more source
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai +12 more
wiley +1 more source
The relation between cerebral morphological abnormalities in major depressive disorder and antidepressant treatment [PDF]
Yaya Sun
openalex +1 more source
CDGSH iron sulfur domain 1 (CISD1) mitigates oxidative stress by promoting NADH oxidation and Coenzyme Q (CoQ) reduction. Under chronic stress, elevated CISD1 expression in microglia enhances NAD⁺ production, thereby increasing GAPDH activity and glycolytic flux, while reducing ATP synthesis by inhibiting proton transfer from mitochondrial complexes I ...
Wanting Dong +5 more
wiley +1 more source
Case Report: Case report : Mindfulness training led to catharsis and mindfulness-to-meaning in a patient with social anxiety disorder comorbid with persistent depressive disorder (Dysthymia) [PDF]
Hisanobu Kaiya +6 more
openalex +1 more source
Novel TMS-derived metrics enable machine learning classification of major depressive disorder. [PDF]
López Pereyra S +3 more
europepmc +1 more source
Generalized Mechanism Model for Ecosystem Hysteresis
A simplified model examines ecosystem transitions into alternative states after disturbances by leveraging positive and negative feedbacks. It identifies critical tipping points and quantifies hysteresis. Tests conducted on lakes, grasslands, and pitcher‐plant leaves align closely with empirical data and enable the prediction of recovery trajectories ...
Yanbin Hao +9 more
wiley +1 more source

