Results 101 to 110 of about 60,901 (141)

Potentiating Cerebral Perfusion Normalizes Glymphatic Dynamics in Systemic Inflammation

Advanced Science, EarlyView.
LPS‐induced systemic inflammation increases glymphatic influx but delays cervical lymphatic drainage, accompanied by AQP4 depolarization and impaired glymphatic clearance. Enhancing cerebral blood flow via the inotropic agent levosimendan effectively restored AQP4 polarization, improving glymphatic flux and amyloid‐β clearance.
Ruoyu Zhao, Bin Sun, Pengju Wei, Yingying Sun, Qianyan He, Kejia Zhang, Jun Lu, Shoujun Zhu, Yi Yang, Zhenni Guo   +9 more
wiley   +1 more source

Estimating causal effects of physical disability and number of comorbid chronic diseases on risk of depressive symptoms in an elderly Chinese population: a machine learning analysis of cross-sectional baseline data from the China longitudinal ageing social survey [PDF]

, 2023
Zhenjie Wang, Han‐Mo Yang, Chenxi Sun, Shenda Hong   +3 more
openalex   +1 more source

Synergistic Modulation of Microglial Polarization by Acteoside and Ferulic Acid via Dual Targeting of Nrf2 and RORγt to Alleviate Depression‐Associated Neuroinflammation

Advanced Science, EarlyView.
Machine‐learning‐directed phytochemical pair ACT/FA, administered at BDD's orthodox ratio, synergistically modulates microglial polarization via dual Nrf2/RORγt targeting to attenuate neuroinflammation and depressive behaviors. This concentration‐dependent synergism replicates the parent formula's efficacy while providing a mechanistic basis for ...
Dongjing Guo, Qiancheng Mao, Xinyu Fang, Liuxuan Huang, Haoquan Tian, Wenguang Yang, Feiyue Zhou, Ke Ma   +7 more
wiley   +1 more source

The association between insulin resistance, metabolic variables, and depressive symptoms in Mexican‐American elderly: A population‐based study

, 2017
Breno S. Diniz, Susan P. Fisher‐Hoch, Joseph B. McCormick   +2 more
openalex   +2 more sources

Internet-based treatment for adults with depressive symptoms: the protocol of a randomized controlled trial [PDF]

, 2007
Lisanne Warmerdam, Annemieke van Straten, Pim Cuijpers   +2 more
openalex   +1 more source

Precuneus abnormalities in middle-aged to older adults with depressive symptoms: An analysis of BDI-II symptom dimensions

, 2017
Sarah M. Szymkowicz, Vonetta M. Dotson, Molly E. McLaren, Liselotte De Wit, Deirdre O’Shea, Francis T. Talty, Andrew O’Shea, Eric C. Porges, Ronald A. Cohen, Adam J. Woods   +9 more
openalex   +2 more sources

Association among obesity, insulin resistance, and depressive symptoms: a mediation analysis

BMC Psychiatry
Background The mechanistic role of insulin resistance(IR) between obesity and Depressive Symptoms has long been debated. Objective This study aims to explore the relationship between BMI and Depressive Symptoms to investigate the mediating role of IR in ...
Guoqiang Xiao, Chenghua Lin, Qiaoyu Lan, Zitong Huang, Chumeng Zhou, Jiajia Hu, Ying Cui, Lujie Wang, Borong Zhou   +8 more
doaj   +1 more source

Depressive symptoms are not associated with predementia CSF amyloid pathology

Dementia and Geriatric Cognitive Disorders Extra
INTRODUCTION: Depressive symptoms are associated with Alzheimer’s disease (AD), but their neurobiological and neuropsychological correlates remain poorly understood.
Cecilia Magdalena Eriksson, Bjørn-Eivind Kirsebom, Ragna Espenes, Nikias Siafarikas, Knut Waterloo, Arvid Rongve, Per Selnes, Dag Aarsland, Tormod Fladby, Erik Hessen   +9 more
doaj   +1 more source

Intimacy, Libido, Depressive Symptoms and Marital Satisfaction in Postpartum Couples

, 2009
Rose Marie Eckert Kunaszuk, Gloria F. Donnelly   +1 more
openalex   +1 more source

The Relationship Between Depression Symptoms and Anxiety Symptoms During Acute ECT for Patients With Major Depressive Disorder [PDF]

, 2019
Chun‐Jen Huang, Ching‐Hua Lin, Jyh-I Wu, Wei‐Cheng Yang   +3 more
openalex   +1 more source