Results 211 to 220 of about 121,165 (266)

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm   +2 more
wiley   +1 more source

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

open access: yesArthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker   +17 more
wiley   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel   +12 more
wiley   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis Within a Longitudinal Cohort

open access: yesArthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axial spondyloarthritis (axSpA) and to identify factors associated with D2M and TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis ...
Patricia Remalante‐Rayco   +8 more
wiley   +1 more source

Analysis of anxiety levels and perceived satisfaction after a first encounter with human body prosection among nursing undergraduates based on their self‐perceived presession nervousness: An observational study

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Human body prosection practices are a crucial educational tool for learning anatomy. However, the first exposure to donors' material can cause anxiety, which may affect students' learning experiences and emotional adjustment. This observational study aimed to analyze anxiety levels (state and trait) before and after a prosection session in ...
Mónica Grande‐Alonso   +8 more
wiley   +1 more source

Depression symptom patterns

Psychological Medicine, 1982
SynopsisCluster analyses with 60 depressive patients resulted in a division of the patients into 4 groups: (1) one main group of endogenous depressives; (2), (3) two mixed groups, indicating that it is not always possible to distinguish between endogenous and neurotic depression by means of symptoms; (4) one group of neurotic depressives.
P, Matussek, O, Luks, D, Nagel
openaire   +2 more sources

Symptoms of atypical depression

Psychiatry Research, 2001
Studies examining the demographic and clinical features of depressed patients who meet criteria for the atypical features subtype have often yielded conflicting results. The present study sought to evaluate the demographic and clinical correlates associated with each of the five symptoms (mood reactivity, hypersomnia, hyperphagia, leaden paralysis and ...
M A, Posternak, M, Zimmerman
openaire   +2 more sources

Cooperation and depressive symptoms

Journal of Affective Disorders, 2013
Deficits in pro-social cooperation are common in many individuals with mental illnesses such as depression. For decades, researchers have used economic game paradigms to compare cross-cultural cooperative behavior. However, research using economic games to assess cooperative behavior in clinical populations is in the early stages.
C, Brendan Clark   +3 more
openaire   +2 more sources

Adversity and the Symptoms of Depression

International Journal of Social Psychiatry, 1988
Data from a community survey were used to test the proposition that pathological guilt and vegetative symptoms of depression were less likely to be associated with stressful life events and difficulties than non-specific symptoms like tension and worry.
P E, Bebbington, J, Hurry, C, Tennant
openaire   +2 more sources

Major Depressive Disorder and Depressive Symptoms [PDF]

open access: possible, 2022
In professional sport, the mental health of elite athletes is a major concern. Given its high prevalence and the potential for multifaceted and severe consequences, major depressive disorder is one of the greatest concerns with respect to the mental health of elite athletes.
openaire   +1 more source

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