Results 61 to 70 of about 613,493 (265)

The prevalence of depressive symptoms among fathers and associated risk factors during the first seven years of their child’s life: findings from the Millennium Cohort Study

BMC Public Health, 2016
Background Increasing evidence suggests that postnatal paternal depression is associated with adverse emotional, behavioural and cognitive outcomes in children.
Selina Nath, Lamprini Psychogiou, Willem Kuyken, Tamsin Ford, Elizabeth Ryan, Ginny Russell   +5 more
doaj   +1 more source

Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani, Emmanuel Barbeau, Béatrice Lemesle, Emilie Milongo‐Rigal, Sophie Fernandez, Sandrine Charpentier, Jean‐François Albucher, Nicolas Raposo, Fabrice Bonneville, Patrice Péran, Jérémie Pariente   +10 more
wiley   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Depressive Symptoms and Amyloid Pathology

JAMA Psychiatry
ImportanceDepressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association between depressive symptoms and amyloid pathology.ObjectiveTo examine the association between depressive symptoms and ...
Wiels, Wietse A, Oomens, Julie E, Frisoni, Giovanni B, Prabhakar, Sudesh, Ramakers, Inez H, Rodríguez-Rodriguez, Eloy, Ruiz, Agustín, Rüther, Eckart, Selnes, Per, Silva, Dina, Soininen, Hilkka, Spiru, Luiza, Takeda, Akitoshi, Fröhlich, Lutz, Teichmann, Marc, Tijms, Betty M, Teunissen, Charlotte E, Thompson, Loisa I, Vogelgsangs, Jonathan, Vöglein, Jonathan, Waldemar, Gunhild, Wallin, Åsa K, Yannakoulia, Mary, Yi, Dahyun, Gill, Kiran Dip, Zettergren, Anna, Grimmer, Timo, Hildebrandt, Helmut, Hort, Jakub, Itoh, Yoshiaki, Iwatsubo, Takeshi, Klimkowicz-Mrowiec, Aleksandra, Lee, Dong Young, Engelborghs, Sebastiaan, Lleó, Alberto, Martinez-Lage, Pablo, de Mendonça, Alexandre, Meyer, Philipp T, Kapaki, Elisabeth N, Parchi, Piero, Pardini, Matteo, Parnetti, Lucilla, Popp, Julius, Rami, Lorena, Baeken, Chris, Reiman, Eric M, Rinne, Juha O, Rodrigue, Karen M, Sánchez-Juan, Pascual, Santana, Isabel, Sarazin, Marie, Scarmeas, Nikolaos, Skoog, Ingmar, Snyder, Peter J, Sperling, Reisa A, von Arnim, Christine A F, Villeneuve, Sylvia, Wallin, Anders, Wiltfang, Jens, Zetterberg, Henrik, Ossenkoppele, Rik, Verhey, Frans R J, Vos, Stephanie J B, Visser, Pieter Jelle, Jansen, Willemijn J, group, Amyloid Biomarker Study, Boada, Mercè, Initiative, Alzheimer’s Disease Neuroimaging, Alcolea, Daniel, Altomare, Daniele, Baiardi, Simone, Baldeiras, Ines, Bateman, Randall J, Blennow, Kaj, Bottlaender, Michel, den Braber, Anouk, van Buchem, Mark A, Didic, Mira, Byun, Min Soo, Cerman, Jirí, Chen, Kewei, Chipi, Elena, Day, Gregory S, Drzezga, Alexander, Eckerström, Marie, Ekblad, Laura L, Epelbaum, Stéphane, Förster, Stefan, Dubois, Bruno, Fortea, Juan, Freund-Levi, Yvonne, Frings, Lars, Guedj, Eric, Hausner, Lucrezia, Hellwig, Sabine, Huey, Edward D, Jiménez-Bonilla, Julio F, Johnson, Keith A, Juaristi, Ane Iriondo, Fladby, Tormod, Kandimalla, Ramesh, Paraskevas, George, Kern, Silke, Kirsebom, Bjørn-Eivind S, Kornhuber, Johannes, Lagarde, Julien, Landau, Susan M, Legdeur, Nienke, Llibre Guerra, Jorge J, Maserejian, Nancy N, van der Flier, Wiesje M, Marquié, Marta, Minatani, Shinobu, Morbelli, Silvia Daniela, Mroczko, Barbara, Ntanasi, Eva, de Oliveira, Catarina Resende, Olivieri, Pauline, Orellana, Adelina, Perrin, Richard J, Peters, Oliver   +120 more
openaire   +12 more sources

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Prevalence and management of depressive symptoms in coronary heart disease patients and relationship with cardiovascular prognosis: a prospective cohort study

BMC Psychiatry
Aims Depressive symptoms are comorbid with coronary heart disease (CHD). There is a controversial debate about whether screening and intervention for depressive symptoms could improve cardiovascular prognosis.
Yewei Pan, Yequn Chen, Shenglin Wu, Pengxiang Ying, Zishan Zhang, Xuerui Tan, Jinxiu Zhu   +6 more
doaj   +1 more source

Digital Cognitive Testing in Mitochondrial Disease: Validity and Challenges for Clinical Trial Use

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Primary mitochondrial disease is a group of genetic disorders caused by pathogenic variants in nuclear or mitochondrial DNA, often resulting in progressive neurodegeneration and cognitive decline. Current management is primarily supportive, though recent research offers hope for disease‐modifying treatments in the future.
Oksana Pogoryelova, Jan Smeitink, Herma Renkema, Rosabeth White, Frankie Barton, Rachel Lyon, Jane Newman, Aye Moe, Yi Shiau Ng, Grainne Siobhan Gorman   +9 more
wiley   +1 more source

Factors Associated With the Rising Trend in Self‐Reported Cognitive Disability Among U.S. Adults Aged 18–39 From 2013–2024

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon, Ka‐Ho Wong, Mirriam Mananah, Christopher D. Anderson, Ada Fenick, Amy Arnsten, Arman Fesharaki‐Zadeh, James C. McPartland, Mary L. Adams, Kevin N. Sheth   +9 more
wiley   +1 more source

Neurologic Manifestations of Long COVID Affect Adult Females More Severely Than Males

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterize differences in neurologic manifestations of postacute sequelae of SARS‐CoV‐2 infection (Neuro‐PASC) between females and males. Methods Cross‐sectional study of the first consecutive 261 posthospitalization Neuro‐PASC (PNP) and 2068 nonhospitalized Neuro‐PASC (NNP) patients evaluated at the Neuro‐COVID clinic between ...
Hannah Kopinsky, Melissa Lopez, Janet Miller, Millenia Jimenez, Eric M. Liotta, Igor J. Koralnik   +5 more
wiley   +1 more source