Results 181 to 190 of about 55,314 (289)

Peeking behind the carbocation: identification of (alternative) catalytic bases in the class II active site of conifer resin acid diterpene synthases. [PDF]

Biochem J
Raslan AMAA, Peters RJ.
europepmc   +1 more source

Unlocking a Nitrosuccinate Lyase for Decarboxylative Enzymatic Hydronitration

Angewandte Chemie, EarlyView.
The nitrosuccinate lyase CreD catalyzes C–NO2 bond formation using nitrite in water and shows synthetic practicality with high turnover numbers up to 102,000. A combination of protein engineering and computational methods helped to reveal the mechanistic principles that underpin this unique enzymatic activity.
Matteo Aleotti, Hannah Dreisbach, Rémi Corlay, Clara Weber, Tamara Reiter, Wael Elaily, Bastian Daniel, Klaus Zangger, Pedro A. Sánchez‐Murcia, Mélanie Hall   +9 more
wiley   +1 more source

Localized Accumulation of Tri‐n‐Propylamine Prolongs Electrochemiluminescence for Tumor Model Spheroid Analysis

Angewandte Chemie, EarlyView.
Here, we enhance the electrochemiluminescence imaging of cellular spheroids using [Ru(bpy)3]2+/TPrA chemistry. Our strategy, which involves pre‐incubation with TPrA, enables high‐resolution, long‐term visualization of cellular spheroids without phototoxicity.
Vanshika Gupta, Megan L. Hill, Samuel P. Nortz, Yashvi Choudhary, Ashutosh Rana, Jeffrey E. Dick   +5 more
wiley   +2 more sources

Dock & design: engineering specificity for an alternative pimaradiene outcome with the <i>ent</i>-kaurene synthase from <i>Bradyrhizobium japonicum</i>. [PDF]

Chem Sci
Schmidt-Dannert M, Zhang Y, Liang J, Wang Q, Tufts S, Jia M, Tantillo DJ, Siegel JB, Peters RJ.   +8 more
europepmc   +1 more source

An Enantioselective Alkene Aminoarylation to Form Chiral Indolines via Electrostatically‐Directed Palladium Catalysis

Angewandte Chemie, EarlyView.
Enantioselective aminoarylation of ortho‐allyl anilines is achieved under mild conditions. Key to success is the electrostatically‐directed nature of the key aminopalladation step, achieved by using the sulfonated chiral ligand sSPhos on palladium. A detailed study of electronic trends allows tuning of the sulfonamide protecting group to enable good ...
Max Kadarauch, Paul T. Jirsch, H. Erik Diepers, Hamzah Sharif, Robert J. Phipps   +4 more
wiley   +2 more sources

Redox-protonation landscape of indene-annulated perylenes: chemodivergent switching of multistate NIR chromophores. [PDF]

Chem Sci
Wiencierz-Paś A, Moshniaha L, Chmielewski PJ, Lis T, Waliczek M, Kabe R, Stępień M.   +6 more
europepmc   +1 more source

Cobalt‐Catalyzed Radical Ligand Transfer (RLT) Enables Remote‐Markovnikov Hydroamination of Alkenes

Angewandte Chemie, EarlyView.
A cobalt‐catalyzed remote‐Markovnikov 1,3‐hydroamination of allyl carboxylates proceeds through MHAT, 1,2‐radical acyloxy migration (1,2‐RAM), and radical ligand transfer (RLT) from a Co‐N intermediate, providing protected amino alcohols. ABSTRACT Amino alcohols are prevalent in pharmaceuticals, agrochemicals, and functional materials, yet ...
Arman Khosravi, Ho Martin Yuen, Seth Fremin, Nuwan A. Pannilawithana, Nol Supasueb, Yu Zhang, Peng Liu, Ming‐Yu Ngai   +7 more
wiley   +2 more sources

Synthesis of 1,3-Dienes from Alkenes via Alkenyl Thianthrenium Salts. [PDF]

J Am Chem Soc
Müller S, Klask N, Daff A, Ritter T.
europepmc   +1 more source

Entropic Control of the Helicity Inversion Rates of Twisted Metallomacrocycles by Reversible and Regioselective Deprotonation. [PDF]

J Am Chem Soc
Nakajima T, Tashiro S, Ehara M, Shionoya M.   +3 more
europepmc   +1 more source

Selective defluorination of 1,1,1,2-tetrafluoroethane by lithium phosphide reagents.

Dalton Trans
Warsame HR, Demetriou CM, Crimmin MR.
europepmc   +1 more source