Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou +6 more
wiley +1 more source
High-enthalpy Larderello geothermal system, Italy, powered by thousands of cubic kilometres of mid-crustal magma. [PDF]
Lupi M +17 more
europepmc +1 more source
3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu +11 more
wiley +1 more source
Geodetic Constraints on Segment-Scale Slip Rates and Interseismic Coupling Along the Havran-Balıkesir Fault Zone, NW Anatolia, Türkiye. [PDF]
Tiryakioğlu İ +12 more
europepmc +1 more source
Fluorescent BODIPY‐conjugated thiosemicarbazone ligands and their Ga(III), In(III), and Fe(III) complexes, inspired by Triapine, are developed as theranostic agents. Multiphoton FLIM and confocal microscopy in cancer cells and zebrafish reveal real‐time uptake, mitochondrial localisation, and whilst spectroscopic assays indicated preserved complex ...
Megan J. Green +15 more
wiley +1 more source
Machine learning-based method for determining regional parameters of the HSS model: a case study of Qingdao, China. [PDF]
Yuan C +4 more
europepmc +1 more source
A programmable 2048‐element circular ultrasound array combined with a compact acoustic lens produces a thin “sound sheet” over a large field of view, and records echoes with wide angular diversity across the ring aperture. Coherence‐enhanced beamforming converts full‐matrix data into high‐contrast tomographic slices, delivering near‐diffraction‐limited
Qiu‐De Zhang +11 more
wiley +1 more source
InSAR analysis reveals insights into the Ms 6.2 earthquake rupture and tectonic dynamics of the northeast margin of the Qinghai‒Tibet plateau. [PDF]
Sun G, Guo F, Guo X, Li M, Peng B.
europepmc +1 more source
Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
Fault-mediated magma propagation and triggered seismicity revealed by the 2022 São Jorge Azores unrest. [PDF]
Hicks SP +21 more
europepmc +1 more source

