Results 51 to 60 of about 285,137 (292)

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Enhancing water depth inversion accuracy via SAR and variable window sliding segmentation

Frontiers in Marine Science
The utilization of synthetic aperture radar (SAR) for depth inversion is crucial for accurate underwater mapping. However, current SAR-based techniques face challenges in segmentation accuracy, which directly affects inversion precision and spatial ...
Meng Zhang, Meng Zhang, Chao Qi, Chao Qi, Fanlin Yang, Fanlin Yang, Ruifu Wang, Ruifu Wang, Saied Pirasteh, Saied Pirasteh   +9 more
doaj   +1 more source

A new approach for inversion of receiver function for crustal structure in the depth domain

Earth and Planetary Physics, 2022
A method for reconstructing crustal velocity structure using the optimization of stacking receiver function amplitude in the depth domain, named common conversion amplitude (CCA) inversion, is presented.
TianYu Zheng, YuMei He, Yue Zhu
doaj   +1 more source

First detection of the ground-state J_K = 1_0 → 0_0 submillimeter transition of interstellar ammonia [PDF]

, 1983
The J_K = 1_0 → 0_0 transition of ammonia at 572.5 GHz has been detected in OMC-1 from NASA's Kuiper Airborne Observatory. The central velocity of the line (V_(LSR)≈ 9 km s^(-1)) indicates that it originates in the molecular cloud material, not in the ...
Blake, Geoffrey A., Keene, Jocelyn, Phillips, T. G.   +2 more
core  

LC-VCO design optimization methodology based on the gm/ID ratio for nanometer CMOS technologies [PDF]

, 2011
In this paper, an LC voltage-controlled oscillator (LC-VCO) design optimization methodology based on the gm/ID technique and on the exploration of all inversion regions of the MOS transistor (MOST) is presented.
Fiorelli, Rafaella, Peralías Macías, Eduardo, Silveira Noguerol, Fernando   +2 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Magnetotelluric inversion for depth-to-basement estimation [PDF]

SEG Technical Program Expanded Abstracts 2015, 2015
The magnetotelluric (MT) method can be effectively applied for depth-to-basement estimation, because there exists a strong contrast in resistivity between a conductive sedimentary basin and a resistive crystalline basement. Conventional inversions of MT data are usually aimed at determining the volumetric distribution of the conductivity within the ...
Hongzhu Cai*, Michael S. Zhdanov
openaire   +3 more sources

A Noise De-Correlation Based Sun Glint Correction Method and Its Effect on Shallow Bathymetry Inversion

Remote Sensing, 2022
Sun glint on the sea surface is the unavoidable noise in optical remote sensing images. Water depth retrieval based on optical remote sensing images is vulnerable to sun glint contamination.
Aijun Cui, Jingyu Zhang, Yi Ma, Xi Zhang
doaj   +1 more source

Global crustal thickness from neural network inversion of surface wave data [PDF]

, 2007
We present a neural network approach to invert surface wave data for a global model of crustal thickness with corresponding uncertainties. We model the a posteriori probability distribution of Moho depth as a mixture of Gaussians and let the various ...
Andrew Curtis, Aristodemou, Bassin, Benaouda, Bishop, Cornford, Curtis, Curtis, Cybenko, Das, Devilee, Dziewonski, Geman, Hornik, Jeannot Trampert, Komatitsch, Komatitsch, Komatitsch, Lampinen, MacKay, MacKay, Moller, Montagner, Mooney, Mosegaard, Nabney, Neal, Ritzwoller, Ritzwoller, Roth, Rumelhart, Sambridge, Sambridge, Shapiro, Shapiro, Tanimoto, Tarantola, Tarantola, Thodberg, Trampert, Ueli Meier, van der Baan, Villaseñor, Webb, Woodhouse, Zhou, Zhou   +46 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source