Results 131 to 140 of about 337,798 (298)

Compressive Strength Impact on Cut Depth of Granite During Abrasive Water Jet Machining

open access: yesJournal of Manufacturing and Materials Processing
Background: Compared to the conventional method of machining granite, abrasive water jet machining (AWJM) offers several benefits, including flexible cutting mechanisms and machine efficiency, among other possible advantages.
Isam Qasem   +2 more
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen   +7 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Statistical Analysis of Burr Width and Height in Conventional Speed Micro-Milling of Titanium Alloy (Ti-6Al-4V) by Varying Cutting Parameters Under Different Lubrication Methods: Dry, MQL and Wet

open access: yesEngineering Proceedings
In this research, micro-milling of Ti-6Al-4V has been carried out in the conventional machining range. The influence of key machining parameters, including feed rate, cutting speed, depth of cut, and cooling conditions, was statistically analyzed in ...
Gulfam Ul Rehman   +5 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao   +5 more
wiley   +1 more source

Morphology of the Te Tumu Cut Under the Potential Re-diversion of the Kaituna River

open access: yes, 2012
Following the diversion of the Kaituna River from Maketū Estuary, out to sea at Te Tumu in 1956, the local community has continually voiced concerns over the estuary’s increased sedimentation rates and decreasing ecological health.
Mawer, Joshua Carl
core  

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

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