Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Human activity recognition is known as the backbone of the development of interactive systems, such as computer games. This process is usually performed by either vision-based or depth sensors.
Raana Esmaeeli +3 more
doaj +1 more source
Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara +10 more
wiley +1 more source
Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Secure Clustering Protocols in Wireless Sensor Networks [PDF]
Wireless sensor networks (WSNs) are poised of huge number of low-cost and tiny devices i.e. senor nodes which communicate over wireless media. Various WSN based projects produced fruitful and interesting results that greatly improves our life.
Sharma, S C, SINGH, SANTAR PAL
core
Hybrid Orientation Based Human Limbs Motion Tracking Method
One of the key technologies that lays behind the human–machine interaction and human motion diagnosis is the limbs motion tracking. To make the limbs tracking efficient, it must be able to estimate a precise and unambiguous position of each tracked human
Grzegorz Glonek, Adam Wojciechowski
doaj +1 more source
Banana Pseudostem Width Detection Based on Kinect V2 Depth Sensor. [PDF]
Wang J, Li X, Zhou Y, Wang H, Li M.
europepmc +1 more source
The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński +12 more
wiley +1 more source
Event‐driven system for fall detection using body‐worn accelerometer and depth sensor
The authors present efficient and effective algorithms for fall detection on the basis of sequences of depth maps and data from a wireless inertial sensor worn by a monitored person.
Michal Kepski, Bogdan Kwolek
doaj +1 more source
Structural Design of Ocean Temperature and Depth Sensor with Quick Response and High Sensitivity. [PDF]
Liu Z +8 more
europepmc +1 more source

