Results 31 to 40 of about 368,727 (301)
Obligatory third party liability insurance for professionals
For several years obligatory third party liability insurance are getting more and more popular in Poland. Polish legislator obliged many professional groups to have such insurance.
Diana Renata Bożek
doaj +1 more source
Deregulation with consensus [PDF]
In this paper the authors analyze the problem of eliminating an inefficient regulation that keeps prices artificially high while obtaining consensus from all agents involved. The planner designs an optimal mechanism to maximize a weighted sum of incumbent finins profits and consumer surplus.
Sandro Brusco, Hugo Hopenhayn
openaire +3 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Conflits et négociations au Havre avant et après les grandes réformes portuaires
Contrary to what many observers expected, the two main port reforms implemented in Le Havre (1992 and 2008), far from reducing the numbers and combative spirit of the Le Havre dockers' union, have strengthened it.
John Barzman
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Précaires sur les pistes aéroportuaires
European airline deregulation policies have led to greater outsourcing of ground handling services and caused in turn a casualisation of labour. Facing the segmentation of work groups and given the uncertainty that accompanies flexible work, management ...
Fabien Brugière
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
For an uninterrupted power supply, renewable energy promises to be a suitable alternative compared to the conventional sources. System delays or communication delays may cause significant synchronization imbalances between various components in big ...
Soumen Biswas +3 more
doaj +1 more source

