Results 81 to 90 of about 437,480 (390)

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Professional financial and accounting services in the light of European Union directives and the deregulation of professions in Poland – current status and research needs

Copernican Journal of Finance & Accounting, 2015
The article describes the issue of the impact of legislative changes on the market of professional accounting and financial services. It discusses the scope and essence of the changes both to the directives of the European Union and the deregulation of ...
Marlena Ciechan-Kujawa
doaj  

miR2Disease: a manually curated database for microRNA deregulation in human disease

Nucleic Acids Res., 2008
‘miR2Disease’, a manually curated database, aims at providing a comprehensive resource of microRNA deregulation in various human diseases. The current version of miR2Disease documents 1939 curated relationships between 299 human microRNAs and 94 human ...
Qinghua Jiang, Yadong Wang, Y. Hao, Liran Juan, Mingxiang Teng, Xinjun Zhang, Meimei Li, Guohua Wang, Yunlong Liu   +8 more
semanticscholar   +1 more source

Deposit deregulation [PDF]

Depository Institutions Deregulation and Monetary Control Act of 1980 ; Depository Institutions Deregulation Committee ; Bank ...
Jack Beebe
core  

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

THE EFFECT OF MARKET REGULATION ON NEWLY PRIVATIZED STATE-OWNED COMPANIES [PDF]

Analele Universităţii Constantin Brâncuşi din Târgu Jiu : Seria Economie, 2014
Before the ’70s the regulation economy was focused on antitrust laws. In 1962, the economists George Stigler and Claire Friedland [1] shaped the regulation idea on state-owned utilities companies (especially in the energy sector).
BODISLAV DUMITRU-ALEXANDRU
doaj  

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Quo vadis, Energiewenderecht?

TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2019
Die Energiewende betrifft als Transformationsprozess eine Vielzahl von Beteiligten: Unternehmen, Forschung, Verbraucher*innen und den Gesetzgeber. Letzterer kann ein erheblicher Treiber oder ein vehementer Bremser der Energiewende sein.
Michael Kalis, Lars Dittmar
doaj   +1 more source

COMMERCIAL BANKS' RESPONSE TO COSTLY DEPOSITS IN A DEREGULATED ENVIRONMENT [PDF]

The study examines balance sheet changes at Texas commercial banks following the 1980 bank deregulation. A comparison of selected deposit and asset variables for 1978 (pre-deregulation) and 1987 (post- deregulation) reveals a rapid increase in costly ...
Betubiza, Eustacius N., Leatham, David J.   +1 more
core   +1 more source

E-cadherin can limit the transforming properties of activating β-catenin mutations [PDF]

, 2015
Wnt pathway deregulation is a common characteristic of many cancers. But only Colorectal Cancer predominantly harbours mutations in APC, whereas other cancer types (hepatocellular carcinoma, solid pseudopapillary tumours of pancreas) have activating ...
Alan R Clarke, Alastair Watson, Andrew D Campbell, Ann Hedley, Aoife Maguire, Brendan Doyle, David J Huels, Fatih Ceteci, Fei Song, Gabriela Kalna, Guenievre Moreaux, James Matthews, Karen R Reed, Lee Parry, Lionel Larue, Marc Leushacke, Nick Barker, Ola Söderberg, Owen J Sansom, Rachel A Ridgway, Runjan Chetty, Serra S, Simon Leedham, Sorina Radulescu, Sparks AB, Stefano Serra, Sujata Biswas, Valerie S Meniel   +27 more
core   +2 more sources