On discontinuity of derivations, inducing inequivalent complete metric topologies
Extracta MathematicaeWe give an elementary method for constructing commutative Fréchet algebras with non-unique Fréchet algebra topology. The result is applied to show that the action of any non-algebraic analytic function may fail to be uniquely defined among other useful ...
S.R. Patel
doaj
The chemistry of connective tissues. 2. Soluble proteins derived from partial hydrolysis of elastin [PDF]
, 1955 S. M. Partridge +2 more
openalex +1 more source
Molecular Oncology, EarlyView.The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine +10 more
wiley +1 more source
A Novel Nomogram to Differentiate Between Renal Tuberculosis and Nontuberculous Renal Infection. [PDF]
Infect Drug ResistLiu P, Qin Y.
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Predicting hemorrhage expansion in patients with hypertensive intracerebral hemorrhage: the HE-VSD-A2TP score. [PDF]
Front NeurolZhu Y +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Development and internal validation of the PROFIT and POSITIVE prognostic nomograms for patients undergoing VA-ECMO therapy. [PDF]
Sci RepQian S, Li P, Hou X, Dong N.
europepmc +1 more source
Molecular Oncology, EarlyView.In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton +17 more
wiley +1 more source
A Serum DLL1 and CRP dual-marker model for bacterial infection detection in patients with decompensated cirrhosis: A dual-cohort diagnostic study. [PDF]
Sci ProgHuang J +6 more
europepmc +1 more source