Results 211 to 220 of about 6,167,674 (361)

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

Development and validation of nomograms for aneurysm rupture risk and prognosis in Moyamoya disease with intracranial aneurysms. [PDF]

Sci Rep
Wang C, Cao L, Sun K, Dong Y, Wang H, Li D, Zhao C, Zhang M, Li H, Yang B.   +9 more
europepmc   +1 more source

The chemistry of connective tissues. 3. Composition of the soluble proteins derived from elastin [PDF]

, 1955
S. M. Partridge, H. F. Davis
openalex   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Development, validation, and updating of prognostic models for m7G-associated genes from TAMs in lower-grade gliomas. [PDF]

Sci Rep
Ao L, Li H, Zhang K, Li M, Liu H, Tang Z.   +5 more
europepmc   +1 more source

CLXXIX.—Hydrizino-halides derived from oxalic acid [PDF]

, 1905
Douglas Anderson Bowack, Arthur Lapworth
openalex   +1 more source

Guarded commands, nondeterminacy and formal derivation of programs

Communications of the ACM, 1975
E. Dijkstra
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

A novel feature extractor based on constrained cross network for detecting sleep state. [PDF]

Sci Rep
Tian C, Song F.
europepmc   +1 more source

INTERSPECIFIC HYBRIDS IN CREPIS. III. CONSTANT FERTILE FORMS CONTAINING CHROMOSOMES DERIVED FROM TWO SPECIES [PDF]

, 1929
James L. Collins, Lillian Hollingshead, P. J. Avery   +2 more
openalex   +1 more source