Results 221 to 230 of about 5,342,052 (371)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Clinical risk score to predict poor coronary collateralization in type 2 diabetic patients with chronic total occlusion. [PDF]

open access: yesBMC Cardiovasc Disord
Mao LS   +10 more
europepmc   +1 more source

In Vitro and In Vivo Studies on a Tissue Culture Cell Line Derived from Normal Monkey Heart [PDF]

open access: bronze, 1958
L.L. Coriell   +5 more
openalex   +1 more source

Derivation in Germanic

open access: yes
Derivational word-formation processes play an important role in the Germanic languages. In particular, prefixation and suffixation are highly productive. In accordance with the so-called right-hand head principle, suffixes tend to determine the morphological category of a word, and are therefore often category-changing (e.g.
openaire   +1 more source

The roles and applications of extracellular vesicles in cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicles (EVs) are minute versions of cells limited by a lipid bilayer containing cytoplasm from the cell that releases them, but without a nucleus and thus unable to self‐reproduce. EVs contain multiple molecules (proteins, lipids, glycans, and nucleic acids) they can induce complex responses in cells.
Clotilde Théry, Daniel Louvard
wiley   +1 more source

On discontinuity of derivations, inducing inequivalent complete metric topologies

open access: yesExtracta Mathematicae
We give an elementary method for constructing commutative Fréchet algebras with non-unique Fréchet algebra topology. The result is applied to show that the action of any non-algebraic analytic function may fail to be uniquely defined among other useful ...
S.R. Patel
doaj  

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