Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
A Novel Classification and Regression Tree-Driven Decision Tree Combining Neutrophil-to-Lymphocyte Ratio and C-reactive Protein for Early Prognostication of Severe Acute Pancreatitis: A Prospective Vietnamese Cohort Study. [PDF]
Huynh TM +4 more
europepmc +1 more source
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
sFlt-1/PlGF ratio thresholds for diagnosing pre-eclampsia in pregnant women with high blood pressure. [PDF]
Pan X +6 more
europepmc +1 more source
Early Prediction of Paroxysmal Atrial Fibrillation in Patients With Acute Stroke Using the BANQMR Score. [PDF]
Suzuki S +9 more
europepmc +1 more source
Reverse shock index multiplied by Glasgow Coma Scale score as a predictor of urgent trauma care and mortality in isolated severe traumatic brain injury: a 10-year nationwide validation study. [PDF]
Kokeguchi H +4 more
europepmc +1 more source
Continuous indices to assess the phenotypic spectrum of kidney transplant rejection. [PDF]
Vaulet T +30 more
europepmc +1 more source
LEAST as a novel prediction model of hepatocellular carcinoma development in patients with chronic hepatitis B: a multi-center study. [PDF]
Song J +12 more
europepmc +1 more source
Intravascular ultrasound-guided percutaneous coronary intervention in acute coronary syndrome stratified by the TVF-ACS risk score: the IVUS-ACS trial. [PDF]
Kan J +22 more
europepmc +1 more source

