Results 181 to 190 of about 959,671 (288)

Proteomic Risk Score for Prediction of Incident Hypertension. [PDF]

Hypertension
Kim M, Tavolinejad H, Sarmiento Bustamante M, Segers P, Neirynck RE, De Meyer T, De Buyzere ML, Rietzschel E, Chirinos JA.   +8 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Deep-learning networks accurately detect pulmonary hypertension in patients with idiopathic pulmonary fibrosis. [PDF]

ERJ Open Res
Arvanitaki A, Diller GP, Lawrence A, Mukherjee B, Semple T, Kouranos V, Li W, Gatzoulis MA, Price LC, Wort SJ.   +9 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Diaphragm Contraction Pressure Index: A New Forecasting Indicator for Weaning from Mechanical Ventilation. [PDF]

Int J Gen Med
Zhang P, Jiang H, Li Z, Zhou Q, Wu J, Wang M, Wu J, Jiang X.   +7 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Beyond proof-of-concept: Validating robust automated diffuse lower-grade glioma segmentation for clinical applications in longitudinal follow-up. [PDF]

Neurooncol Adv
Deverdun J, Clain G, Verdier M, Duffau H, Van Dokkum LEH, Menjot de Champfleur N, Meriadec J, Carriere M, Darlix A, Le Bars E.   +9 more
europepmc   +1 more source

On Derived and Integral Basic Sets of Polynomials [PDF]

Proceedings of the American Mathematical Society, 1954
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Derivation and validation of a machine learning-driven score to predict the diagnostic yield of endomyocardial biopsy. [PDF]

NPJ Digit Med
Basile C, Polte CL, Gentile P, Bollano E, Rawshani A, Oldfors A, Ljungman C, Bartfay SE, Dahlberg P, Hjalmarsson C, Björkenstam M, Gualini E, Cannatá A, Pedrotti P, Garascia A, Savarese G, Maggioni AP, Karason K, Bobbio E.   +18 more
europepmc   +1 more source