Results 211 to 220 of about 5,311,848 (309)

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Disorder-specific alterations of transient oscillatory dynamics during sleep across cortical and subcortical networks. [PDF]

Sci Rep
Biabani N, Ilic K, Birdseye A, Ivanenko O, Higgins S, Rosenzweig J, Cvetkovic Z, Nesbitt AD, Mutti C, Parrino L, Naismith S, Drakatos P, Morten K, O'Regan D, Goadsby PJ, Leech R, Rosenzweig I.   +16 more
europepmc   +2 more sources

Concurrent Multi-Beam Digital Predistortion Using FFT Beamforming and Virtual Arrays. [PDF]

Sensors (Basel)
Langborn B, Fager C, Hou R, Eriksson T.
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Clinical Context Variables Collectively Rival Model Choice in Embedding-Based Retrieval: Multi-Corpus Benchmark Study. [PDF]

JMIR Med Inform
Mikkelsen Y.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Ictal fear of death with preserved context dependent speech and postictal amnesia in focal epilepsy. [PDF]

Front Neurol
Saouda C, Kassem-Scott Y, El Hallak E, Hareesh P, Vinarsky V, Eid A, Makke Y, Koubeissi MZ.   +7 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Variance of the root mean square value of the residuals of sine fitting in the presence of additive noise. [PDF]

Sci Rep
Alegria FAC.
europepmc   +1 more source