Results 81 to 90 of about 2,368,464 (368)

Efficient Fourth-Order Scheme for Multiple Zeros: Applications and Convergence Analysis in Real-Life and Academic Problems

open access: yesMathematics, 2023
High-order iterative techniques without derivatives for multiple roots have wide-ranging applications in the following: optimization tasks, where the objective function lacks explicit derivatives or is computationally expensive to evaluate; engineering ...
Sunil Kumar   +2 more
doaj   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

open access: yesMolecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke   +12 more
wiley   +1 more source

Higher-Order Multiplicative Derivative Iterative Scheme to Solve the Nonlinear Problems

open access: yesMathematical and Computational Applications, 2023
Grossman and Katz (five decades ago) suggested a new definition of differential and integral calculus which utilizes the multiplicative and division operator as compared to addition and subtraction.
Gurjeet Singh   +2 more
doaj   +1 more source

A Family of Multi-Asset Automated Market Makers [PDF]

open access: yesarXiv, 2021
We present a family of multi-asset automated market makers whose liquidity curves are derived from the financial principles of self financing transactions and rebalancing. The constant product market maker emerges as a special case.
arxiv  

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale   +9 more
wiley   +1 more source

A generalization of the rational rough Heston approximation [PDF]

open access: yesQuantitative Finance, 2024, 2023
Previously, in [GR19], we derived a rational approximation of the solution of the rough Heston fractional ODE in the special case \lambda = 0, which corresponds to a pure power-law kernel. In this paper we extend this solution to the general case of the Mittag-Leffler kernel with \lambda \geq 0.
arxiv  

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

open access: yesMolecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou   +13 more
wiley   +1 more source

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

open access: yesMolecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran   +16 more
wiley   +1 more source

Flexural Behavior of Bidirectionally Graded Lattice

open access: yesAdvanced Engineering Materials, EarlyView., 2023
An experimental study of the bending behavior of bidirectional body‐centered cubic lattice beams is conducted in comparison to uniform and unidirectional counterparts of electron beam melted SS 316 L. Experimental results are used to develop and validate a finite element model which is subsequently used to conduct parametric studies to assess the ...
Chamini Rodrigo   +4 more
wiley   +1 more source

Analysis of a Four-Dimensional Hyperchaotic System Described by the Caputo–Liouville Fractional Derivative

open access: yesComplexity, 2020
A new four-dimensional hyperchaotic financial model is introduced. The novelties come from the fractional-order derivative and the use of the quadric function x4 in modeling accurately the financial market.
Ndolane Sene
doaj   +1 more source

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