Advanced Science, EarlyView.In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei +17 more
wiley +1 more source
Comparative Physicochemical Characterization of Polylactic Acid-Based Dermal Fillers. [PDF]
Polymers (Basel)Su CY, Chang YC, Cheng PJ, Fang HW.
europepmc +1 more source
Advanced Science, EarlyView.Paraventricular CRF neurons in the hypothalamus project to glutamatergic neurons of the spinal trigeminal caudal nucleus, enhancing neuronal activation and CRFR2 signaling. This pathway increases CRF release and excitatory drive, promoting central sensitization and migraine‐related behaviors. Targeting the PVN–SP5C circuit provides a potential strategy
Jiang Bian +13 more
wiley +1 more source
Real-World Usage of CaHA-CMC:CPM-HA Hybrid Dermal Fillers: Findings From a Delphi Panel. [PDF]
J Cosmet DermatolKadouch J +8 more
europepmc +1 more source
Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions
Advanced Science, EarlyView.This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang +4 more
wiley +1 more source
Modulating rheology and bioactivity in dermal fillers: the emerging role of platelet-rich plasma (PRP). [PDF]
Front Med (Lausanne)Anitua E, Tierno R, Alkhraisat MH.
europepmc +1 more source
Printable Conductive Hydrogels for Electrochemical Biosensing and Soft Bioelectronic Interfaces
Advanced Science, EarlyView.Flexible, conductive hydrogels that integrate printability, mechanical tunability, biocompatibility, and electronic performance remain challenging to achieve. Here, we develop 3D‐printable poly(ethylene glycol)–poly(pyrrole)‐ hydrogels with tissue‐like mechanics, high cytocompatibility, and robust electrochemical function.
Lukas Hein +6 more
wiley +1 more source
Understanding Clinical and Biophysical Differences Between Non-Cross-Linked and Cross-Linked Hyaluronic Acid Dermal Fillers. [PDF]
J Cosmet DermatolFontenete S +3 more
europepmc +1 more source
The Intrinsic Relation between the Hydrogel Structure and In Vivo Performance of Hyaluronic Acid Dermal Fillers: A Comparative Study of Four Typical Dermal Fillers. [PDF]
Tissue Eng Regen Med, 2023 Zhou W +7 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Self‐healing materials represent a paradigm shift in designing functional biomedical devices for drug delivery, tissue regeneration, and 3D bioprinting. However, their clinical translation remains limited by challenges such as insufficient mechanical strength, potential cytotoxicity from chemical modifications, and complex activation ...
Ganjun Feng +15 more
wiley +1 more source