Prenatal mold exposure is associated with development of atopic dermatitis in infants through allergic inflammation [PDF]
Objective: Mold exposure in early life may be associated with development of atopic dermatitis; however, studies of this link are inconclusive and evidence for the underlying mechanism(s) is lacking. This study identified the association between the time
Eun Lee +12 more
doaj +4 more sources
ADAPTAÇÃO TRANSCULTURAL E VALIDAÇÃO DA ESCALA DE GRAVIDADE DE PRURIDO EM CRIANÇAS E ADOLESCENTES COM DERMATITE ATÓPICA [PDF]
RESUMO Objetivo: Realizar tradução, adaptação e validação da Itch Severity Scale (ISS-Ped) para medir a gravidade de prurido em crianças e adolescentes com dermatite atópica.
Dayanne Mota Veloso Bruscky +2 more
doaj +2 more sources
A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance. [PDF]
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Fernandes B +8 more
europepmc +2 more sources
IMPACTO DA DERMATITE ATÓPICA NA QUALIDADE DE VIDA DE PACIENTES PEDIÁTRICOS E SEUS RESPONSÁVEIS [PDF]
RESUMO Objetivo: Avaliar o impacto da dermatite atópica na qualidade de vida de pacientes pediátricos de 5 a 16 anos e seus responsáveis, atendidos no serviço de dermatologia da Universidade do Estado do Pará (UEPA) em 2015.
Amanda Letícia Bezerra Campos +4 more
doaj +2 more sources
Efficacy of Der f 2/Zen 1-LAMP1 Plasmid-Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof-of-Concept Study. [PDF]
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Bizikova P +6 more
europepmc +2 more sources
Machine Learning Model for an App-Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis. [PDF]
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Langon X, Montoya M, Gourdon I.
europepmc +2 more sources
Randomised, Double-Blinded, Placebo-Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions. [PDF]
ABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Sofou EI +4 more
europepmc +2 more sources
Atopic dermatitis and vitamin D: facts and controversies. [PDF]
Patients with atopic dermatitis have genetically determined risk factors that affect the barrier function of the skin and immune responses that interact with environmental factors.
Mesquita Kde C, Igreja AC, Costa IM.
europepmc +4 more sources
Evaluation of filaggrin 2 expression in dogs with atopic dermatitis before and after oclacitinib maleate administration. [PDF]
Background – Canine atopic dermatitis (cAD) is a chronic, inflammatory, multifactorial and pruritic disease. The presence of skin barrier impairment (e.g. filaggrin alterations), along with abnormal immune responses, can negatively impact cutaneous barrier function.
Villalobos WR +5 more
europepmc +2 more sources
Effect of a Spray Containing Occlusive Agents, Humectants and Physiological Lipids on Skin Hydration of Healthy Dogs When Applied After Bathing With a Chlorhexidine 2%/Miconazole 2% Shampoo. [PDF]
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Pseftogka A +3 more
europepmc +2 more sources

