Results 101 to 110 of about 71,525 (243)
Allergy, EarlyView.This study investigates mutual interaction of skin microbes and surface lipids in AD using the advanced method of shotgun lipidomics with ultra‐broad coverage of lipids and 16S amplicon sequencing of tape strips taken from lesional and non‐lesional AD and healthy controls.
Madhumita Bhattacharyya +14 more
wiley +1 more source
Allergy, EarlyView.This study analyzed data from a sub‐cohort of the MEDALLION study to examine the association between maternal adherence to the Mediterranean diet and the development of food allergy in offspring. Maternal dietary intake during pregnancy and lactation was assessed using the validated MedDiet Score, together with individual food group consumption ...
Emilia Vassilopoulou +11 more
wiley +1 more source
Examining Atopic Dermatitis Through the One Health Concept Lens
Allergy, EarlyView.ABSTRACT This paper explores the application of the One Health framework to atopic dermatitis (AD), a complex, chronic skin disease, emphasizing interdisciplinary approaches to prevention and management. One Health integrates human, animal, environmental, and plant health, addressing challenges such as antimicrobial resistance, infectious diseases, and
Dijana Minić‐Pantić +10 more
wiley +1 more source
Single Cell Analysis Reveals Dynamic Changes of Distinct Cell Populations in Human Nickel Allergy
Allergy, EarlyView.We investigated cell types mediating the early and late inflammatory responses in human Ni2+‐allergy by scRNA‐Seq. Early responsiveness was mainly mediated by TLR4+TAGLN− endothelial cells indirectly activating TLR4−KRT16+ keratinocytes, and CCR7+DCN+ DCs. Late responsiveness was crucially driven by infiltration of KLF2+ central memory T cells and TLR4+
Marc Schmidt +7 more
wiley +1 more source
Allergy, EarlyView.This study explores the bidirectional associations between SD and EBDs in a cohort of 5,083,689 individuals in a US administrative claims database. Positive bidirectional associations were found between SD and many EBDs of the skin, respiratory, gastrointestinal, and ocular surfaces. Our results support the EBT as a shared driver of EBD pathogenesis at
Sabrina Meng +6 more
wiley +1 more source
Allergy, EarlyView.This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen). The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.
Nikolina Todorović +14 more
wiley +1 more source
Allergy, EarlyView.Ligelizumab re‐treatment in CSU patients showed sustained efficacy and tolerability. Over 50% achieved symptom control (UAS7 ≤ 6) by Week 12; benefits maintained through Week 52. No new safety signals observed; aligns with prior PEARL trial outcomes. CSU, chronic spontaneous urticaria; mg, milligram; q4w, every 4 weeks; UAS, urticaria activity score ...
Ana M. Gimenez‐Arnau +22 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT The allergy and asthma epidemic in urban societies following World War II is mostly caused by changes in the environment, diet and lifestyle. Disconnection of urban populations from the wider environment has reduced the protective factors building up immunological resilience.
Tari Haahtela +21 more
wiley +1 more source
Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food
Allergy, EarlyView.ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy +7 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Background Atopic diseases—including atopic dermatitis (AD), food allergy (FA), allergic rhinitis (AR), and asthma—are the most common chronic conditions in childhood and adolescence, affecting up to 30% of the global population. In Germany alone, more than 2.1 million children and adolescents are affected.
E. Hamelmann +13 more
wiley +1 more source