Results 171 to 180 of about 1,912,798 (308)

Corticosteroid Exposure in Autoimmune Hepatitis: Early Toxicity, Cumulative Burden and Associations With Long‐Term Patient‐Reported Outcomes

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In a patient‐reported cohort of 565 adults with autoimmune hepatitis, 96.6% reported corticosteroid‐related side effects within 6 months and long‐term toxicity increased with cumulative exposure. The findings support earlier tapering, toxicity monitoring, lower induction dosing when appropriate and selective budesonide use in carefully chosen non ...
Elizabeth Gentry   +4 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Contact dermatitis.

open access: yesNagoya journal of medical science, 2000
openaire   +2 more sources

Peripheral targets for neuropathic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour   +3 more
wiley   +1 more source

The fight of innate immunity and abnormal cannabinoids against Candida infection

open access: yesBritish Journal of Pharmacology, EarlyView.
Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori   +2 more
wiley   +1 more source

Non-Invasive Transcriptomic Profiling of Inflammatory Skin Diseases Using Four Tape Strips. [PDF]

open access: yesInt J Mol Sci
Vinge AS   +5 more
europepmc   +1 more source

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