Results 201 to 210 of about 2,211,574 (368)

Recombinant Hypoallergenic Cat Allergy Vaccines

open access: yesAllergy, EarlyView.
This study reports the construction and preclinical characterization of peptide‐carrier‐based vaccines combining all three important cat allergens (Fel d 1, Fel d 4 and Fel d 7) within single vaccine antigens, termed PreS‐Cat 1‐PreS‐Cat 5. Two subcutaneous immunizations of rabbits with PreS‐Cat 1‐5 induce equal or better antibodies blocking allergic ...
Daria Trifonova   +17 more
wiley   +1 more source

Clinical Benefits of a Randomized Allergy App Intervention in Grass Pollen Sufferers: A Controlled Trial

open access: yesAllergy, EarlyView.
Different functions of an allergy app were tested for clinical benefit in a randomized, controlled trial in patients with grass pollen allergy. Participants with pollen forecast function took more medication and had fewer symptoms than participants without pollen forecast. A symptom forecast was developed based on the study data.
Caroline Holzmann   +13 more
wiley   +1 more source

Role of kappa‐opioid and mu‐opioid receptors in pruritus: Peripheral and central itch circuits

open access: yesExperimental Dermatology, Volume 31, Issue 12, Page 1900-1907, December 2022., 2022
Abstract Modern genetic approaches in animal models have unveiled novel itch‐specific neural pathways, emboldening a paradigm in which drugs can be developed to selectively and potently target itch in a variety of chronic pruritic conditions. In recent years, kappa‐opioid receptors (KORs) and mu‐opioid receptors (MORs) have been implicated in both the ...
Brian S. Kim   +5 more
wiley   +1 more source

Contact Dermatitis

open access: yesInternational Journal of Clinical Practice, 1955
openaire   +2 more sources

Relevance of state–behaviour feedbacks for animal welfare

open access: yesBiological Reviews, EarlyView.
ABSTRACT An animal's behaviour and its state, including its health and affective state, are dynamic and tightly coupled, influencing each other over time. Although both are relevant to the animal's welfare, there has been limited research on their dynamics in welfare studies. Here we aim to: (i) review evidence for feedbacks between state and behaviour
Camille M. Montalcini   +2 more
wiley   +1 more source

A Multicenter Phase II Trial of Nimustine Hydrochloride Administered via Convection‐Enhanced Delivery in Children With DIPG

open access: yesCancer Science, EarlyView.
The efficacy of the CED of nimustine hydrochloride in pediatric DIPG was evaluated. One‐year survival rate from the start of radiotherapy was 60%. The treatment strategy demonstrated potential efficacy. ABSTRACT Diffuse intrinsic pontine glioma (DIPG) is a very challenging‐to‐treat pediatric malignant tumor, with a median survival time of < 12 months ...
Ryuta Saito   +13 more
wiley   +1 more source

Fatal mycosis fungoides, misdiagnosed as contact dermatitis. [PDF]

open access: yesEJNMMI Rep
Shadmani G   +2 more
europepmc   +1 more source

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