Results 61 to 70 of about 14,888 (246)

Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema

Allergy, EarlyView.
This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery, Rüçhan Ekren, Emilie Bérard, Aurélie Du‐Thanh, Hugo Rimet, Fatma Jendoubi, Vanina Lenief, Nadia Raison‐Peyron, Amel Bouznad, Maria P. Konstantinou, Jonathan Rioual, Lilian Basso, Juliette Mouiren, Manon Boussier, Brigitte Milpied, Cristina Bulai Livideanu, Louise Jaulent, Florence Hacard, Marine A. Lefevre, Audrey Nosbaum, Julien Seneschal, Marc Vocanson, Carle Paul, Nicolas Gaudenzio, Marie Tauber, on behalf of the French Atopic Dermatitis Network from de GREAT Research group   +25 more
wiley   +1 more source

Glove-Induced Hand Dermatitis: A Study in Healthcare Workers during COVID-19 Pandemic in Indonesia

Dermatology Research and Practice, 2023
Skin damage among healthcare workers has been reported by many centers around the world. Occupational hand dermatitis is one of the most commonly known occupational skin diseases and a socially significant health issue.
Cita Rosita Sigit Prakoeswa, null Damayanti, Sylvia Anggraeni, Menul Ayu Umborowati, Fajar Waskito, Niken Indrastuti, Sri Awalia Febriana, Agnes Rosarina Prita Sari, Kristo Alberto Nababan, Cut Putri Hazlianda, null Nopriyati, Windy Keumala Budianti, Miranti Pangastuti, Faridha Ilyas, Agnes Kartini, Nurwestu Rusetiyanti, Ika Anggraini, Idrianti Idrus, Herwinda Brahmanti, Gardenia Akhyar   +19 more
doaj   +1 more source

Patch Test Results With the European Baseline Series, 2021/2022-Joint European Results of the ESSCA^A and the EBS^B Working Groups of the ESCD, and the GEIDAC^C. [PDF]

Contact Dermatitis
ABSTRACT Background Patch test results obtained with the European Baseline Series (EBS) in its current version serve both contact allergy surveillance and (re‐)assessing the diagnostic value of EBS allergens. Objectives To present results of current EBS patch testing, obtained in 59 departments in 14 European countries during 2021 and 2022.
Uter W, Wilkinson SM, Aerts O, Bauer A, Borrego L, Brans R, Buhl T, Dickel H, Dugonik A, Filon FL, Arnau AG, Patruno C, Pónyai G, Gregoriou S, Schubert S, Simon D, Stingeni L, Valiukevičienė S, Weisshaar E, Werfel T, Gonçalo M, Schuttelaar MA, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC .   +23 more
europepmc   +2 more sources

Prevalence of Occupational Contact Dermatitis and its related Factors among Surgical Technologists in Five Educational Centers of Mazandaran University of Medical Sciences

بهداشت کار و ارتقای سلامت, 2021
Introduction: Occupational skin diseases and hand contact dermatitis specifically are among the most common occupational diseases among the healthcare workers.
ali PAHNABI, Solale RAMAZANI, Ehsan MOHAMMADI, Ebrahim NASIRI   +3 more
doaj  

Occupational airborne contact dermatitis caused by trifluoroacetic acid in an organic chemistry laboratory

, 2019
airborne; allergic contact dermatitis; laboratory workers; occupational; organic chemistry; trifluoroacetic ...
최유원, 최혜영, 변지연
core   +1 more source

Rapid Human Skin Barrier Disruption by Sodium Dodecyl Sulfate and Associated Molecular Mechanisms

Allergy, EarlyView.
Short‐term exposure to SDS rapidly disrupts human skin barrier integrity within minutes, as detected by real‐time electrical impedance spectroscopy. SDS‐induced barrier dysfunction is driven by oxidative stress, leading to suppression of immune/barrier mediators and activation of stress, lipid remodeling, and epidermal differentiation pathways ...
Manru Li, Huseyn Babayev, Paolo D'Avino, Can Zeyneloğlu, Ceren Bicer, Duygu Yazici, Yagiz Pat, Per Svedenhag, Nicolas Gaudenzio, Cezmi A. Akdis, Yasutaka Mitamura   +10 more
wiley   +1 more source

Keratinocyte Priming by Staphylococcus aureus Reduces HSV‐1 Susceptibility

Allergy, EarlyView.
ADEH+ patients have a reduced microbial diversity with increased S. aureus and S. epidermidis colonization compared to ADEH− and healthy controls. Heat‐killed S. aureus reduced HSV‐1 susceptibility and release of infectious progeny virus in a keratinocyte in vitro model. Heat‐killed S.
Phila Cara Baumann, Rebecca Pospich, Katinka Döhner, Ilona Klug, Julio Cesar Villalvazo Guerrero, Jan Hartmann, Inken Harder, Wolfgang Lieb, Barbara Kind, Andreas Kleinheinz, Susanne Abraham, Matthias Augustin, Elke Weisshaar, Jochen Schmitt, Stephan Weidinger, Beate Sodeik, Thomas Werfel, Lennart M. Roesner, Stephan Traidl, The TREATgermany Study Group   +19 more
wiley   +1 more source

Occupational dermatoses reported in Brazil from 2007 to 2014 [PDF]

Anais Brasileiros de Dermatologia, 2018
: Background: Occupational diseases are very prevalent in the world, especially in developing countries. Occupational dermatoses are responsible for most of these cases. However, epidemiological studies are rare in Brazil.
Michelle Larissa Zini Lise, Fernando Ribas Feijó, Michael Laurence Zini Lise, Claudia Ribeiro Zini Lise, Luis Carlos Elejalde de Campos   +4 more
doaj   +1 more source

Advancing the understanding of allergic contact dermatitis: from pathophysiology to novel therapeutic approaches

Frontiers in Medicine, 2023
Allergic contact dermatitis (ACD) is a common inflammatory skin disease that, especially when the condition becomes chronic, has a high impact on the quality of life and represents a significant disease burden.
Marta Tramontana, Katharina Hansel, Leonardo Bianchi, Chiara Sensini, Nicolò Malatesta, Luca Stingeni   +5 more
doaj   +1 more source

Contact sensitisers activate keratinocytes and induce cytotoxicity via Transient Receptor Potential Ankyrin 1 in allergic contact dermatitis

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Allergic contact dermatitis (ACD) is a frequent inflammatory skin disease with limited therapeutic options. While neuronal Transient Receptor Potential Ankyrin 1 (TRPA1) has been implicated in ACD, the role of keratinocyte TRPA1 remains unclear.
Areej Jaber, Szabina Horváth, Balázs Zoltán Zsidó, Viktória Kormos, János Konkoly, Csaba Hetényi, Erika Pintér, Ágnes Kemény, Rolland Gyulai   +8 more
wiley   +1 more source