Results 121 to 130 of about 425,664 (357)

Cytotoxic Activity of Opopanax hispidus (Friv.) Griseb.: Characterization of a New Chalcone‐type Compound

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The present study aimed to investigate cytotoxic compounds of Opopanax hispidus (Friv.) Griseb. through in vitro, in silico, and phytochemical analyses. The cytotoxic activity of O. hispidus was evaluated against four different cancer cell lines – lung (A549), breast (MCF‐7), liver (HepG2), and cervix (HeLa) – as well as one healthy cell line (
Kevser Taban   +7 more
wiley   +1 more source

Dressing a Demanding Body to Fit In: Clean and Decent with Ostomy or Chronic Skin Disease

open access: yesSocial Inclusion, 2019
This article discusses what kind of strategies people with a stoma or various chronic skin conditions, such as psoriasis or atopic dermatitis, use to find clothes that fit and enable them to fit in. Based on qualitative interviews in Norway, we study how
Kirsi Laitala, Ingun Grimstad Klepp
doaj   +1 more source

Plinia cauliflora Leaf Extract Promotes Wound Healing Through Anti‐Inflammatory, Antioxidant, and Antibacterial Actions

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT Plinia cauliflora (DC.) Kausel (jabuticaba) is traditionally used by Brazilian indigenous communities for therapeutic purposes, including the treatment of wounds and inflammation. This study investigated the phytochemical composition and biological activities of an ethanolic extract derived from P.
Priscila de Lima Paula   +17 more
wiley   +1 more source

Inmunoterapia con alérgenos: mecanismos de acción, impacto terapéutico y socioeconómico. Consenso de la Asociación Colombiana de Alergias, Asma e Inmunología

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2016
Las alergias constituyen un conjunto de enfermedades de gran prevalencia. Cuando los procesos alérgicos no se controlan, pueden poner en peligro la salud e, incluso, la vida de los pacientes y, además, su efecto económico y social es considerable.
Jorge Sánchez   +9 more
doaj   +1 more source

Relative Bioavailability, Food Effect, and Bioequivalence Studies to Assess a New Zanubrutinib 160‐mg Tablet: Results From 2 Phase 1 Studies in Healthy Volunteers

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Zanubrutinib is a next‐generation Bruton tyrosine kinase inhibitor approved for treating B‐cell malignancies. Two phase 1 studies evaluated a new 160‐mg zanubrutinib tablet versus 80‐mg capsules. In study BGB‐3111‐115 (n = 43), a randomized 3‐period crossover trial, relative bioavailability and food effects were assessed.
Bilal Tariq   +5 more
wiley   +1 more source

A Phase 1, Randomized, Open‐Label, Parallel Group Study to Evaluate the Relative Bioavailability and Safety of Subcutaneous Bepirovirsen when Delivered from a Vial or Prefilled Syringe Fitted with a Safety Syringe Device in Healthy Adult Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract Bepirovirsen, an antisense oligonucleotide in development for the treatment of chronic hepatitis B virus (HBV) infection, is administered from glass vials as a subcutaneous (SC) injection by healthcare professionals (HCPs). A ready‐to‐use prefilled syringe (PFS) assembled with a safety syringe device (SSD) has been developed to make ...
Amir S. Youssef   +15 more
wiley   +1 more source

Therapeutic Potential of Lebrikizumab in the Treatment of Atopic Dermatitis

open access: yesJournal of Asthma and Allergy, 2020
Tiffany Y Loh,1 Jennifer L Hsiao,2 Vivian Y Shi1 1University of Arizona, Division of Dermatology, Tucson, AZ, USA; 2University of California Los Angeles, Division of Dermatology, Los Angeles, CA, USACorrespondence: Vivian Y ShiDivision of Dermatology ...
Loh TY, Hsiao JL, Shi VY
doaj  

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